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agelaea coccinea/tricin

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Tricin from a malagasy connaraceous plant with potent antihistaminic activity.

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The bioassay-guided separation of a Malagasy plant, Agelaea pentagyna, led to the isolation of a flavonoid, tricin (1), with potent inhibitory activity toward exocytosis from antigen-stimulated rat leukemia basophils (RBL-2H3). The structure-activity relationships among structurally related natural
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