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ajuga/necrosis

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iRhom2 (Uncv) mutation blocks bulge stem cells assuming the fate of hair follicle.

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iRhom2 is necessary for maturation of TNFα-converting enzyme, which is required for the release of tumor necrosis factor. In the previous study, we found that the iRhom2 (Uncv) mutation in N-terminal cytoplasmic domain-encoding region (iRhom2 (Uncv) ) leads to aberrant hair shaft and inner root
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