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Page 1 from 174 results
The use of radiolabelled human serum albumin and SPECT/MRI co-registration to study inflammation in the cavernous sinus of cluster headache patients.
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A sterile inflammation in the cavernous sinus was hypothesized to underlie cluster headache (CH). Neurogenic inflammation is accompanied by the extravasation of plasma proteins in the surrounding tissue. We tested the hypothesis of an inflammatory process in the cavernous sinus in CH patients using
Comment on "The use of radiolabelled human serum albumin and SPECT/MRI coregistration to study inflammation in the cavernous sinus of cluster headache patients" by Schuh-Hofer et al.
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Effects on urinary albumin excretion and renal function changes by delapril and manidipine in normotensive type 2 diabetic patients with microalbuminuria.
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This study was designed to investigate the effect of delapril, an ACE inhibitor, and manidipine, a long action calcium antagonist, on persistent microalbuminuria in normotensive type 2 diabetic patients. Sixty type 2 diabetic patients were randomized to take delapril 30 mg/day or manidipine 10
Risk Factors for Developing Postlumbar Puncture Headache: A Case-Control Study
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Background: Postlumbar puncture headache (PLPH) is a common adverse event after lumbar puncture. The specific cause for headache remains uncertain but is assumed to be cerebrospinal fluid leakage. The headache affects the patient, family,
Octocog alfa, antihaemophilic factor (recombinant), plasma/albumin free method (Advate®): a review of its use in the management of patients with haemophilia A.
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Octocog alfa, antihaemophilic factor, plasma/albumin free method (Advate®) is a recombinant, human, full-length coagulation factor VIII that does not contain human- or animal-derived plasma proteins. It is indicated for the control and prevention of bleeding episodes, for perioperative management
Intravenous albumin infusion is an effective therapy for hyponatremia in patient with malignant ascites.
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There are few reports about the treatment of moderate to severe hyponatremia associated with malignant liver metastasis. Here, we report using intravenous salt poor albumin infusion to treat hypervolemic cirrhosis related hyponatremia. A 58-year-old female with ascites secondary to metastatic breast
A Phase I/II study evaluating escalating doses of recombinant human albumin-interferon-alpha fusion protein in chronic hepatitis C patients who have failed previous interferon-alpha-based therapy.
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Albumin-interferon-alpha (IFN-alpha) is a novel 85.7-kDa recombinant protein consisting of IFN-alpha that is genetically fused to human serum albumin. In this Phase I/II, multicentre, open-label study, we evaluated the safety and tolerability, pharmacokinetics and pharmacodynamics of
A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients.
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OBJECTIVE
Recombinant human albumin-interferon alfa (alb-IFN) is a novel 85.7-kD recombinant protein consisting of interferon alfa-2b genetically fused to human serum albumin.
METHODS
A phase 2, open-label, dose-ranging study was conducted in IFN-alfa-naïve patients with genotype 1 chronic hepatitis
Urinary albumin excretion as a marker of endothelial dysfunction in migraine sufferers: the HUNT study, Norway.
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OBJECTIVE
To investigate urine albumin leakage as a marker of endothelial dysfunction in migraine patients.
METHODS
A population-based health study.
METHODS
303 patients with migraine, 1009 patients with non-migraine headache and 5287 headache-free controls.
RESULTS
The association between urine
Is there a correlation between spreading depression, neurogenic inflammation, and nociception that might cause migraine headache?
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The time course of propagation of scotoma and blood flow changes during migraine aura parallels the phenomenon of cortical spreading depression (CSD). It was proposed that CSD generates a sterile neurogenic inflammation in the meninges, which may then lead to the activation or sensitization of
Cluster headache is not associated with signs of a systemic inflammation.
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OBJECTIVE
To investigate whether there is clinical or biochemical evidence for a transient systemic inflammation during active periods of cluster headache.
METHODS
Twenty-seven male and female consecutively selected patients with episodic cluster headache filled in questionnaires aiming at detecting
Is low blood magnesium level associated with hemodialysis headache?
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OBJECTIVE
The aim of this study was to evaluate the prevalence, demographic, clinical features, and possible risk factors for hemodialysis headache (HDH).
BACKGROUND
HDH has been recognized for many years, but the pathophysiology of this condition is not known. High arterial blood pressure,
Hemodialysis headache.
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OBJECTIVE
The aim of this study was to evaluate and analyze the incidence and features of headaches in patients undergoing hemodialysis.
METHODS
In this prospective study 318 patients, 119 women and 199 men, undergoing chronic HD in four hemodialysis centers in Serbia, were questioned about their
Levels of nitric oxide metabolites in cerebrospinal fluid in cluster headache.
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The pathophysiology of cluster headache (CH) is only partly understood. Nitric oxide (NO), a potent vasodilator, has been suggested to be involved, and increased plasma levels of nitrite, a stable product on NO degradation, have been identified in the active period and in remission. The aim of our
Cluster headache in the male: sex steroid pattern and gonadotropic response to luteinizing hormone releasing hormone.
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Serum testosterone, dihydrotestosterone, delta 4-androstendione and 17 beta-estradiol, sex hormone binding globulin (SHBG) and gonadotropic response to luteinizing hormone releasing hormone (LHRH) were studied in 34 male subjects with episodic or chronic cluster headache (CH). The sex steroid free
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