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allopurinol/fever
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Sapacitabine, Cyclophosphamide, Rituximab for Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma (CLL/SLL) With Deletion (11q22-23)
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The Study Drugs:
Sapacitabine and cyclophosphamide are designed to damage the DNA (genetic material) of cancer cells, which may cause the cancer cells to die.
Rituximab is designed to attach to cancer cells and damage them, which may cause the cancer cells to die. It is also designed to cause the
Autologous Hematopoietic Cell Transplantation for Core-binding Factor (CBF) Acute Myeloid Leukemia (AML) in the First Complete Remission (CR1)
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5.2 AUTOLOGOUS PBSCS HARVESTING
5.2.1. PBSCs will be collected during recovery phase after the second cycle of HDAC consolidation chemotherapy.
5.2.2. For mobilization, recombinant human granulocyte- colony-stimulating factor (G-CSF, Filgrastim) will be given subcutaneously at a dose of 10 mcg/kg
Busulfan Plus Cyclophosphamide vs Fludarabine as a Conditioning Regimen
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1. TREATMENT PLAN
- The patients will be admitted to laminar air flow room.
- The patients will have triple lumen Hickman central venous catheter (CVC) placed. Vancomycin 1 gm IV immediately prior to CVC placement and 1 gm q 12 hours for 3 doses. Chest X-ray should be taken after CVC placement to
a Phase II Study in Primary Central Nervous System Lymphoma
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5 PATIENT SELECTION 5.1 Eligibility Criteria
Patients must fulfill all the following criteria to be eligible for admission for the study:
1. Histologically proven central nervous system lymphoma of brain parenchyma with or without leptomeningeal involvement.
2. No evidence of systemic lymphoma.
3.
Safety Study: Combined Modality Treatment for Non-Small Cell Lung Cancer
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Lung cancer is the leading cause of cancer death in both men and women in the United States. It is estimated that there are over 170,000 new cases of lung cancer in the United States and over 150,000 deaths annually. Surgical excision is currently the treatment of choice for patients with operable
Thymoglobuline in Non-myeloablative Allogeneic Stem-cell Transplantation
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Allogeneic stem cell transplantation (SCT) from a fully matched donor is the treatment of choice for a growing number of malignant and non-malignant indications. Until recently, myeloablative in conjunction with immunosuppressive conditioning was considered mandatory for the elimination of malignant
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