aminophylline/obesity

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Effects of ephedrine and aminophylline on resting energy expenditure in obese adolescents.

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The thermogenic effect of ephedrine (E) and aminophylline (AP) was investigated in 27 and 20 obese adolescents by indirect calorimetry. Ten children receiving only water served as controls. Nine children from both groups had no thermic response to the drugs (NR). The responders (R) increased their

[Effect of aminophylline, a phosphodiesterase inhibitor on somatotropin secretion after intravenous tolbutamide loading in obese subjects].

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[Behavior of IRI after carbohydrate and aminophylline stimulation in normal, obese and diabetic subjects].

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Theophylline clearance: effect of marked obesity.

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Total body clearance (ClT) of theophylline was examined in 12 markedly obese patients and related to total body weight (TBW) and ideal body weight (IBW). Patients were infused with aminophylline continuously and evaluated at steady state. Total body clearances of theophylline were 29.5 +/- 7.8

Theophylline disposition in obesity.

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Theophylline disposition was examined in 14 obese subjects and 57 normal subjects. A single oral dose of aminophylline solution was given and serum and saliva samples were collected over several hours and assayed by high-pressure liquid chromatography. The apparent volume of distribution (Vd) and

Aminophylline loading in asthmatic patients: a protocol trial.

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We tested an aminophylline loading-dose protocol in which asthmatic patients presenting to an emergency department were given a half (3 mg/kg) IV loading dose based on total body weight (TBW) if they had taken a short-acting or sustained-release theophylline preparation within 12 or 24 hours,

Lipid mobilization in subcutaneous adipose tissue during exercise in lean and obese humans. Roles of insulin and natriuretic peptides.

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The aim of this study was to evaluate the relative contributions of various hormones involved in the regulation of lipid mobilization in subcutaneous adipose tissue (SCAT) during exercise and to assess the impact of obesity on this regulation. Eight lean and eight obese men performed a 60-min cycle

Enhancement of cold-stimulated thermogenesis in the corpulent rat (LA/N cp) by aminophylline.

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Previous studies on obese strains of rats (e.g., Zucker and LA/N cp) have shown that they are deficient in nonshivering thermogenesis and poor in cold tolerance. Our earlier studies have established that aminophylline (AMPY; 85% theophylline-15% ethylenediamine) is effective in significantly

Drug-induced cardiotoxicity due to aminophylline treatment: a case report.

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BACKGROUND Aminophylline, a theophylline compound that contains ethylenediamine, has untoward side effects on many organ systems. OBJECTIVE The goal of this case report was to illustrate the occurrence of acute adverse events (ie, chest discomfort and myocardial enzyme elevation) that may be

Glycerol release in vitro from adipose tissue of obese (ob/ob) mice treated with thyroid hormones.

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Glycerol release from adipose tissue of adult genetically obese (ob/ob) mice was greater than that from adipose tissue of lean litter-mates. However, a higher concentration of adrenaline was required to stimulate lipolysis in ob/ob adipose tissue. Since oxygen consumption and the uptake of

Regional fat loss from the thigh in obese women after adrenergic modulation.

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Beta-adrenergic stimulation and alpha 2-adrenergic inhibition increase lipolysis from fat cells. Twenty-eight obese women were placed on a calorie-restricted diet and one of five treatments was applied to one thigh three to five times per week for four weeks: (1) isoproterenol injections; (2) cream

Insulin secretion in the obese (ob/ob) mouse. The effect of oxytetracycline on insulin release.

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The effect of oxytetracycline (OTC) pretreatment on the response of the ob/ob mouse to insulin secretagogues in vivo and in vitro was investigated. With glucose loading in vivo, the peak glucose was twofold greater and the insulin levels threefold greater in obese than in lean mice. After OTC

[Obesity and hypoventilation syndrome; effects of weight loss and treatment with respiratory stimulants].

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A 32-year-old, hypertensive, morbidly obese (BMI 49 kg/m2) woman was referred to us suspected of sleep-disordered breathing. Polycythaemia, right heart and respiratory failure, restrictive ventilatory impairment, decreased hypercapnic respiratory drive, high number of very short apneas mostly of

Lack of arrhythmogenicity of aminophylline in dogs.

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This study was designed to determine if doses of aminophylline up to 10 mg/kg given i.v. would produce ventricular arrhythmias in seven healthy dogs anaesthetized with fentanyl-droperidol-pentobarbital. Arrhythmias were sought by inspection of ECGs before and after attempts at provoking them with 5

The failure of aminophylline to modulate glucagon release in man.

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There are conflicting results regarding the impact of cyclic AMP on pancreatic glucagon release. The effect of aminophylline, a phosphodiesterase inhibitor, on glucagon secretion was studied in four non-obese, non-diabetic, healthy young male volunteers. The subjects received separate infusions of:

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