analgesic/fatigue

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Naloxone reverses inhibitory effects of fatigue and of compounds not related to narcotic analgesics in the guinea-pig ileum.

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A novel GABAB receptor positive allosteric modulator, ASP8062, exerts analgesic effects in a rat model of fibromyalgia.

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The gamma-aminobutyric acid type B (GABA_B) receptor agonist, the sodium salt of gamma-hydroxybutyrate (GHB), significantly improved pain, sleep disturbance and fatigue in fibromyalgia (FM) patients. However, the use of GABA_B receptor agonists is limited by their undesirable

Female gender is a risk factor for pain, discomfort, and fatigue after laparoscopic groin hernia repair.

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OBJECTIVE Female gender is a risk factor for early pain after several specific surgical procedures but has not been studied in detail after laparoscopic groin hernia repair. The aim of this study was to compare early postoperative pain, discomfort, fatigue, and nausea and vomiting between genders

Zolpidem reduces postoperative pain, fatigue, and narcotic consumption following knee arthroscopy: a prospective randomized placebo-controlled double-blinded study.

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Sixty-eight patients undergoing outpatient knee arthroscopy for treatment of meniscal tears or loose bodies were divided into three treatment groups (zolpidem [24 patients], control [24 patients], and placebo [20 patients]). All groups received postoperative hydrocodone and ibuprofen. Patients in

Analgesic nephropathy: an underestimated cause of end-stage renal disease.

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Addiction and abuse of antipyretic analgesics has been recognized early after the turn of this century. The incidence markedly increased and the syndrome spread over many countries in the first half of the 20th century. The syndrome and its pathology, consisting of renal papillary necrosis and

A cluster of high psychological and somatic symptoms in children with idiopathic scoliosis predicts persistent pain and analgesic use 1 year after spine fusion.

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BACKGROUND Persistent postoperative pain is a significant problem for many children, particularly for those undergoing major surgery such as posterior spine fusion. More than two-thirds report persistent pain after spine fusion, yet factors that may contribute to poorer outcomes remain poorly

The Relationship between Parental Factors, Child Symptom Profile and Persistent Postoperative Pain Interference and Analgesic Use in Children

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Objectives: Both parental and child factors have been previously associated with persistent or recurrent postoperative pain in children. Yet, little is known about the relative contribution of parent factors or whether child symptom

[The effect of the analgesic flupirtine on automobile driving].

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The purpose of the present study was to investigate the effects on driving ability of the new analgesic ethyl-N-(2-amino-6-(4-fluor-phenylmethylamino) pyridin-3-yl) carbamate (flupirtine, D 9998) in comparison with pentazocine and placebo. Flupirtine was tested in a double blind cross-over

Laparoscopic-assisted or laparoscopic-facilitated sigmoidectomy for diverticular disease? A prospective randomized trial on postoperative pain and analgesic consumption.

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OBJECTIVE Laparoscopic-assisted sigmoidectomy is an attractive but sometimes challenging operative technique for the treatment of diverticulitis of the sigmoid colon. The aim of this study was to compare, with respect to early postoperative analgesic demand and postoperative pain,

A thought for tramadol hydrochloride as labor analgesic.

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OBJECTIVE To evaluate and compare the analgesic efficacy and adverse effects of tramadol and meperidine in labor. METHODS One hundred sixty-three of the 213 parturients at term in active labor were randomly assigned to one of three groups to receive intramuscularly either tramadol 50 mg (N = 54),

Multidimensional independent predictors of cancer-related fatigue.

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The purpose of this study was to identify independent predictors of clinically significant fatigue based upon a multidimensional model. A total of 180 cancer patients completed the Brief Fatigue Inventory (BFI), Functional Assessment of Cancer Therapy-Fatigue (FACT-F), Memorial Symptom Assessment

The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study.

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BACKGROUND Gabapentin is an anticonvulsant drug that has analgesic properties for acute postoperative pain. However, the analgesic effect of gabapentin as an antiepileptic prophylactic drug on patients undergoing craniotomy is unclear. In this study, we evaluated the postoperative effectiveness of

Use of ketorolac after lower abdominal surgery. Effect on analgesic requirement and surgical outcome.

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BACKGROUND Ketorolac is a nonsteroidal antiinflammatory agent with opioid-sparing properties. The effect of ketorolac on postoperative opioid analgesic requirement and surgical outcome was evaluated in 198 women after abdominal hysterectomy procedures using a double-blind protocol

Compassion fatigue and substance use among nurses.

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UNASSIGNED This study aimed to detect if there were differences in compassion fatigue (CF) among nurses based on substance use and demographic variables of gender, marital status, type of health institution and income. UNASSIGNED Compassion fatigue is considered an outcome of poorly handled

Dexamethasone does not reduce pain or analgesic consumption after thyroid surgery; a prospective, randomized trial.

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BACKGROUND Post-operative analgesic effect of a perioperative fixed dose glucocorticoid has been demonstrated in studies on different surgical procedures. The aim of this study was to look for analgesic and opioid sparing effect after thyroid surgery with a weight-adjusted medium dose of

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