antibacterial/fever

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Bactericidal action of a complement-independent antibody against relapsing fever Borrelia resides in its variable region.

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A single chain variable fragment (scFv) of CB515, a complement-independent bactericidal monoclonal IgM against a relapsing fever Borrelia, was constructed to investigate the region wherein the unique bactericidal function resides. Monomeric CB515 scFv (26 kDa) was capable of binding its Ag on whole

Generation of a complement-independent bactericidal IgM against a relapsing fever Borrelia.

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The spirochetemia of relapsing fever in mice is cleared by a complement-independent, polyclonal IgM response with reactivity to two prominent Ags of 20 and 35 kDa. In this study, we have dissected the polyclonal IgM Ab response against a relapsing fever spirochete to determine the specificity of its

Modification of bactericidal effects of microwave heating and hyperthermia by hydrogen peroxide.

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Two different approaches for studying of bactericidal effects of microwave heating and hyperthermia were introduced. Low concentration of hydrogen peroxide (0.05%) was used to modify the sensitivity of isogenous strains of Escherichia coli K-12 to microwave heating and hyperthermia with the

Furazolidone in typhoid fever--correlation of clinical efficacy with serum bactericidal activity.

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Treatment of typhoid fever with furazolidone produces a high cure rate. This is a clinical curiosity, as furazolidone is described to be poorly absorbed. The present study examined whether furazolidone could produce unequivocal clinical response and, if so whether this was due to the drug producing

[Modern views on the efficacy of different antibacterial preparations in the treatment and prophylaxis of inflammatory processes in patients after transurethral local ultrasonic hyperthermia of the prostate].

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Extensive clinical investigation was accomplished to study the influence of three antibacterial preparations groups (tetracyclines, aminoglycosides and fluorochinolons) on the phagocytic-macrophages and the immune systems in patients, to whom transurethral local microwave hyperthermia (TLMH) of

A simple bactericidal antibody test for sero-diagnosis of typhoid fever.

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Serum samples were collected from 24 confirmed cases of typhoid fever, 15 clinically suspected cases and 23 normal healthy controls. The convalescent sera were obtained in 13 of the 24 confirmed typhoid cases. In all, 13 paired sera, 11 acute phase only, 15 clinically suspected and 23 normal serum

Antibodies to lipooligosaccharide of a Brazilian purpuric fever isolate of Haemophilus influenzae biogroup aegyptius lack bactericidal and protective activity.

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The immunological basis for protection against Brazilian purpuric fever (BPF), a fulminant infection of young children associated with bacteremia with Haemophilus influenzae biogroup aegyptius, is unknown. Candidate antigens to which protective antibodies may be directed include cell surface

Hyperthermia and human leukocyte functions: effects on response of lymphocytes to mitogen and antigen and bactericidal capacity of monocytes and neutrophils.

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It has recently been demonstrated that fever, or hyperthermia, results in enhanced survival of lizards infected by Aeromonas hydrophila. In the present study, the effects of hyperthermia on certain immune functions were assayed in vitro with purified human leukocytes. Lymphocyte transformation

Enhancement of the antibacterial property of amniotic fluid by hyperthermia.

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The intrinsic ability of human amniotic fluid to prevent growth of Escherichia coli varies with the test strain employed, but is enhanced by increasing the temperature of incubation, as demonstrated by viable counts of test organisms in amniotic fluid compared with growth media at various

Antibody to a 145-kilodalton outer membrane protein has bactericidal activity and protective activity against experimental bacteremia caused by a Brazilian purpuric fever isolate of Haemophilus influenzae biogroup aegyptius. The Brazilian Purpuric Fever Study Group.

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The immunologic basis for protection against Brazilian purpuric fever, a septicemic infection associated with Haemophilus influenzae biogroup aegyptius bacteremia, is unknown. Passive immunization of infant rats with antiserum to whole bacterial cells of the homologous strain protects them from

Bacteriostatic and bactericidal activity of levofloxacin against Rickettsia rickettsii, Rickettsia conorii, 'Israeli spotted fever group rickettsia' and Coxiella burnetii.

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Levofloxacin, the L-isomer of ofloxacin, is approximately twice as active as ofloxacin against most Gram-positive and Gram-negative bacteria, and has improved intracellular pharmacokinetic and pharmacodynamic properties. The present work deals with the in-vitro activity of levofloxacin against the

Antibacterial activity of black tea (Camelia sinensis) extract against Salmonella serotypes causing enteric fever.

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Alcoholic extract of black tea (Camelia sinensis) was assayed for its antibacterial activity against Salmonella serotypes causing enteric fever viz., Salmonella typhi and Salmonella paratyphi A. While all strains of S. paratyphi A tested were found sensitive, only 42.19% of S. typhi strains were

Cutting edge: the spirochetemia of murine relapsing fever is cleared by complement-independent bactericidal antibodies.

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Abs are the major effectors of host defense against infections with BORRELIA: Bactericidal murine mAbs and their Fabs destroy B. burgdorferi, the agent of Lyme disease, and relapsing fever Borrelia in the absence of complement. These in vitro observations led to the expansion of a search for

Hyperthermia effect and antibacterial efficacy of Fe3+ /Co2+ co-substitutions in β-Ca3 (PO4 )2 for bone cancer and defect therapy.

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The combined effect of cobalt and iron substitutions in β-Ca3 (PO4 )2 as a potent material for application in hyperthermia and as a bone substitute is presented. Structural analysis reveals the preferential accommodation of Co2+ and Fe3+ at the Ca2+ (5) sites of β-Ca3 (PO4 )2 until the limit of ∼10

Dual-modality self-heating and antibacterial polymer-coated nanoparticles for magnetic hyperthermia.

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Multifunctional nanoparticles for magnetic hyperthermia which simultaneously display antibacterial properties promise to decrease bacterial infections co-localized with cancers. Current methods synthesize such particles by multi-step procedures, and systematic comparisons of antibacterial properties

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