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anticoagulant/inflammation
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Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a novel class of heterocyclic compounds useful for selectively inhibiting trypsin-like enzymes, selectively inhibiting chymotrypsin-like enzymes, selectively inhibiting elastase or for generally inhibiting serine
Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a novel class of heterocyclic compounds useful for selectively inhibiting trypsin-like enzymes, selectively inhibiting chymotrypsin-like enzymes, selectively inhibiting elastase or for generally inhibiting serine
Locally-active anticoagulants and anti-inflammatory agents
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FIELD OF THE INVENTION
The present invention is related to novel thrombin inhibitors as anti-thrombotic agents and locally-active anticoagulants and anti-inflammatory agents.
BACKGROUND OF THE INVENTION
Thrombotic complications constitute major life-threatening conditions for both the aging
Chromatographic purification of human proteins having anticoagulant and anti-inflammatory activity
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TECHNICAL FIELD
The present invention relates to the production and use of proteins in general, and more specifically, to the production of novel proteins exhibiting anticoagulant and anti-inflammatory activity, DNA sequences encoding these proteins, and the use of these proteins in warmblooded
Heparin cofactor II fragments with anti-inflammatory and anti-coagulant activity
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Phase application under 35 U.S.C. .sctn.371 of International Application No. PCT/GB2010/001780 filed Sep. 21, 2010 and claims the benefit of Great Britain Application No. 0916578.8 filed Sep. 22, 2009, the disclosures of which
System and method of extracorporeally treating blood to alleviate the symptoms of inflammatory diseases
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to an extracorporeal blood circulation system for treating inflammatory diseases. More particularly, the present invention is concerned with an extracorporeal blood circulation system for treating inflammatory
Anti-infective and anti-inflammatory releasing systems for medical devices
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BACKGROUND OF THE INVENTION
This invention relates to invasive medical devices for delayed/sustained release of pharmaceutical compositions from a polymer that is coated or incorporated into the devices. The purpose of the coating or delivery system on these devices is to reduce, control or even
Antibodies to IL-6 to inhibit or treat inflammation
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The sequence listing in the file named "43272ol1805.txt" having a size of 341,671 bytes that was created Apr. 3, 2014 is hereby incorporated by reference in its entirety.
BACKGROUND
1. Field of the Art
This invention is an extension of Applicants' prior invention disclosed in the above-referenced
Sulfated oligosaccharide derivatives
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TECHNICAL FIELD
The invention described herein relates to compounds having activity as inhibitors of heparan sulfate-binding proteins, including the enzyme heparanase. In particular, the invention is directed to sulfated oligosaccharide derivatives, although the scope of the invention is not
Solution and method for adhering suspension components to a substrate
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TECHNICAL FIELD
This disclosure relates generally to analyzing a suspension and, in particular, to a solution and method for adhering a component of a suspension to a substrate.
BACKGROUND
Current diagnostic methods and techniques rely on the interpretation of histological and cytological samples.
Solution and method for adhering suspension components to a substrate
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TECHNICAL FIELD
This disclosure relates generally to analyzing a suspension and, in particular, to a solution and method for adhering a component of a suspension to a substrate.
BACKGROUND
Current diagnostic methods and techniques rely on the interpretation of histological and cytological samples.
Sulfated oligosaccharide derivatives
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TECHNICAL FIELD
The invention described herein relates to compounds having activity as inhibitors of heparan sulfate-binding proteins and as inhibitors of the enzyme heparanase. In particular, the invention is directed to sulfated oligosaccharide derivatives, although the scope of the invention is
Sulfated oligosaccharide derivatives
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TECHNICAL FIELD
The invention described herein relates to compounds having activity as inhibitors of heparan sulfate-binding proteins and as inhibitors of the enzyme heparanase. In particular, the invention is directed to sulfated oligosaccharide derivatives, although the scope of the invention is
Isocoumarins with cationic substituents
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a novel class of heterocyclic compounds useful for selectively inhibiting trypsin-like enzymes, selectively inhibiting chymotrypsin-like enzymes, selectively inhibiting elastase or for generally inhibiting serine
Simukunin
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BACKGROUND
Certain medical conditions, such as strokes, cardiovascular blockages, deep vein thrombosis, and pulmonary embolism, are treated with the administration of an anticoagulant, to prevent the formation of blood clots and the extension of existing clots. A widely used anticoagulant is
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