arbusculin a/saussurea lappa

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[Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots].

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OBJECTIVE To study chemical constituents from the roots of Saussurea lappa. METHODS Chemical constituents were separated and purified by various techniques such as silica gel column chromatography, Sephadex LH-20 and reversed phase RP-18 column chromatography. Their structures were identified on the

PTP1B inhibitors from Saussrurea lappa.

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A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside

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