Therapeutic effect of the glucoside extracted from the root of Astragalus Membranaceus (AM) was studied in guinea pigs intoxicated with 600 mg/kg doses of Dimethoate (D). Four groups of guinea pigs, each consisting of two males and two females, were treated with (a) D, (b) D + Atropine, and (c) D +
Astragalus mongholicus (AM) is a traditional medicinal herb used as a neuroprotective agent for its anxiolytic, antidepressant, antiamnestic, and antiaggresive effects. However, the mechanisms underlying its anti-convulsant properties are not well studied. In the present study, we examined the
BACKGROUND
In traditional medicine, Astragalus mongholicus (AM) has been used for the treatment of general weakness, chronic illness, and to increase overall vitality.
OBJECTIVE
The present study investigated possible effects of the saponin fraction of AM on the central nervous system. Moreover, its
Extracts of Astragalus lusitanicus Lam. lusitanicus, a European legume very common in southwestern Spain and Portugal, caused in mice acute toxicity, with convulsions and death in a few min, and delayed death after (10-15 days) with first symptoms appearing 6-8 days after a single i.v. dose. The
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