TECHNICAL FIELD
The present invention relates generally to the field of pharmaceutical compositions. More specifically the present invention relates to the pharmaceutical composition for treating gastrointestinal disorders and uses thereof.
BACKGROUND OF THE INVENTION
The human bowel flora is
TECHNICAL FIELD
The present invention relates to novel benzoxazepine derivatives and their salts. More particularly, it relates to novel benzoxazepine derivatives and their salts useful as medicaments for the treatment of anxiety neurosis, phobias, obsessive-compulsive disorders, schizophrenia,
The present invention relates to compounds of formula I
##STR00002## wherein Y is C--R.sup.1'; R.sup.1' is hydrogen or halogen; R.sup.1 is hydrogen or halogen; R.sup.2 is hydrogen, lower alkyl or phenyl; R.sup.4 is hydrogen or lower alkyl; or R.sup.2 and R.sup.4 may form together with the
The present invention relates to compounds of formula I
##STR00001## wherein R.sup.1 is lower alkyl; R.sup.2 is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be in different positions; n is 0, 1 or 2; V/U are independently from each other O or CH.sub.2, wherein V and U cannot be
The present invention relates to compounds of formula I
##STR00001## wherein Y is N or C--R.sup.1'; G is a 5 or 6-membered aromatic or heteroaromatic ring containing 0, 1, 2 or 3 heteroatoms, selected from the group consisting of phenyl, pyridinyl with different N-positions, imidazolyl, pyrazinyl,
This application is a continuation of International Application PCT/EP2015/053785, filed Feb. 24, 2015, which claims benefit of priority to European Application 14156461.7, filed Feb. 25, 2014, each of which is incorporated herein by reference in its entirety.
The present invention relates to
The present invention relates to compounds of formula I
##STR00002## wherein Y is C--R.sup.1; R.sup.1' is hydrogen, F or Cl; R.sup.1 is F or Cl; R.sup.2 is hydrogen or lower alkyl; R.sup.3 is phenyl, pyridinyl or isothiazolyl, wherein the N atom in the pyridinyl group may be in different positions,
FIELD OF THE INVENTION
The present invention relates to organic of general formula I that are positive allosteric modulators (PAMs) of metabotropic glutamate receptor 4 (mGluR4). useful for therapy of diseases associated with aberrant functioning of the mGluR4 receptor.
BACKGROUND OF THE
The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor
The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor
FIELD OF THE INVENTION
The present invention relates to new D.sub.3 dopamine receptor subtype selective ligands of formula (I) and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof which are useful in the therapy and/or prevention of
TECHNICAL FIELD
The present invention relates generally to the field of pharmaceutical compositions. More specifically the present invention relates to the pharmaceutical composition for treating gastrointestinal disorders and uses thereof.
BACKGROUND OF THE INVENTION
Bowel Flora
The human bowel
TECHNICAL FIELD
The present invention relates generally to the field of pharmaceutical compositions. More specifically the present invention relates to the pharmaceutical composition for treating gastrointestinal disorders and uses thereof.
BACKGROUND OF THE INVENTION
Bowel Flora
The human bowel
This application is a national phase patent utility filing under 35 USC .sctn.371, for International (PCT) Patent Application serial no. PCT/AU2010/001410, filed Oct. 22, 2010, which claims benefit of priority to Australian Patent Application Serial No. 2009905229, filed Oct. 26, 2009. The
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