berberis/tyrosine

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Heterologous expression of alkaloid biosynthetic genes--a review.

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Tetrahydrobenzylisoquinoline alkaloids comprise a diverse class of secondary metabolites with many pharmacologically active members. The biosynthesis at the enzyme level of at-least two tetrahydrobenzylisoquinoline alkaloids, the benzophenanthridine alkaloid sanguinarine in the California poppy,

Berbamine: a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity.

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Gleevec, which is an inhibitor of the bcr/abl tyrosine kinase, has been a remarkable success for the treatment of chronic myelogenous leukemia (CML). However, a significant proportion of patients chronically treated with Gleevec develop resistance. Here we describe the activity of a natural small

Berberine alleviates type 2 diabetic symptoms by altering gut microbiota and reducing aromatic amino acids

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Objective: Berberine (BBR), which is extracted from traditional Chinese herb, is abundant in Coptis chinensis and Berberis vulgaris, with a treatment on type 2 diabetes mellitus (T2DM). However, its oral bioavailability is poor.

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