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beta mangostin/breast neoplasms

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Inhibition of CDK2/CyclinE1 by xanthones from the mangosteen ( Garcinia mangostana): a structure-activity relationship study

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Uncontrolled regulation of cyclin dependent kinases (CDKs) has negative implications in many cancers and malignancies and has recently led to the approval of select CDK inhibitors. Herein we present data reporting that xanthones, a class of compounds isolated from the purple mangosteen (Garcinia
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