Current therapy for GBM GBM is the most frequent primary malignant brain tumor in adults. Prior to the introduction of temozolomide, the median survival was generally less than one year from the time of diagnosis. Standard therapy had consisted of surgical resection to the extent safely feasible,
Glioblastoma multiforme is the most malignant and common, about 50%, variant of all primary brain tumours. The treatment strategies for this disease have not changed appreciably for many years consisting of a surgical intervention (biopsy or tumour resection) and post-operative local radiotherapy
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