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Adjuvant therapy for colorectal cancer: yesterday, today, and tomorrow.

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During the 1980s, the only drug routinely used to treat colorectal carcinoma was single-agent fluorouracil (5-FU), a drug that had shown no proven benefit in the adjuvant setting. Since then, significant improvements in the overall management of colorectal cancer have been made. This review will

[Malignant tumors of the female genitalia in childhood--yesterday, today and tomorrow].

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Genital tumors in children and adolescents represent 1.5 to 2.0% of al malignancies in these age groups. Organ incidence differs from that in adult women. In children and in young adolescents non-epithelial gynaecological tumors predominate, while carcinomas are rare and their incidence rises with

High-dose chemotherapy with autologous stem cell rescue for breast cancer: yesterday, today and tomorrow.

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Metastatic breast cancer remains incurable by conventional means and is the second leading cause of all cancer deaths in women in the United States. Laboratory and clinical studies have shown chemotherapy dose intensity may be important in breast cancer therapy, and therefore clinical trials have

Human Tumor Antigens Yesterday, Today, and Tomorrow.

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The question of whether human tumors express antigens that can be recognized by the immune system has been answered with a resounding YES. Most were identified through spontaneous antitumor humoral and cellular immune responses found in cancer patients and include peptides, glycopeptides,

Pancreatic cancer: yesterday, today and tomorrow.

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Pancreatic cancer is one of our most lethal malignancies. Despite substantial improvements in the survival rates for other major cancer forms, pancreatic cancer survival rates have remained relatively unchanged since the 1960s. Pancreatic cancer is usually detected at an advanced stage and most

The Connecticut Tumor Registry: yesterday, today and tomorrow.

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Chemotherapy for ovarian cancer: yesterday, today and tomorrow.

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Cancer of the female breast yesterday, today and tomorrow.

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Cancer cures. Yesterday, today, and tomorrow.

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[Interferons in cancer treatment: yesterday, today and tomorrow].

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[Artificial intelligence in the diagnosis of breast cancer : Yesterday, today and tomorrow].

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Artificial intelligence (AI) is increasingly applied in the field of breast imaging.What are the main areas where AI is applied in breast imaging and what AI and computer-aided diagnosis (CAD) systems are already available?Basic

Laparoscopic interventions in the gut: yesterday, today, and tomorrow.

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The development of laparoscopic interventional surgery has brought about a revolution in general surgery over the past 5 years. Laparoscopic cholecystectomy has now become the treatment of choice for symptomatic cholelithiasis because of a reduction in access trauma, resulting in less postoperative

[Radiation protection in radiation oncology. Yesterday, today, and tomorrow].

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Publications about radiation protection issues are not very frequent in the 100-year-old history of Strahlentherapie und Onkologie. While at the beginning of the last century the problems of radiation protection were determined by the technical development of radiation therapy, the importance of

Selective immmunotherapy through extracorporeal photochemotherapy: yesterday, today, and tomorrow.

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ECP's extensive clinical record, as well as a considerable improvement in the understanding of the mechanism that underlies its efficacy, opens potential novel strategies for the treatment of cancer, GVHD, transplant rejection, and autoimmunity. The low side effect profile of this therapy has made

[Indications for radiotherapy of benign lesions: yesterday, today and tomorrow].

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A better knowledge of the radiobiological effects and the control of the techniques of dosimetry led to a renewed interest for the radiotherapy of the benign lesions. The doses used for these indications are weaker than those recommended for treatment of cancer and the radiobiological mechanisms

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