Recent studies have shown a close association between byssinosis and airborne endotoxin concentrations. Endotoxin might induce byssinosis through the release of biochemical mediators as the broncheoalveolar surface. Alpha-1-antitrypsin (alpha-1-A) which neutralizes enzymes released by granulocytes
The features of the cotton dust syndrome which need to be considered when formulating a hypothesis on mechanism(s) are: 1) the presence of fever, 2) the "Monday effect," 3) the slow onset of forced expiratory volume in 1 second (FEV1) changes, and 4) the presence of bronchitis in chronic sufferers
As part of a 1992 survey of both environmental and occupational determinants of health, 973 non-smoking women aged 20-40 years who were employed in three comparable modern Chinese cotton textile mills were given a questionnaire that included questions on standard respiratory history and symptoms.
The concentration of airborne microbes, their endotoxins and the prevalence of byssinotic symptoms among workers were measured in the cardrooms of seven cotton spinning, a wool spinning and two cotton waste mills and in a dusty workroom of a group of five willowing mills, a tea-packing plant and a
An epidemiological study of 774 workers in seven eastern France cotton textile factories was conducted to determine the prevalence of acute respiratory disorders. From nine non-textile companies, 464 workers, stratified as to sex, age and tobacco consumption participated in the study as a control
Environmental factors which cause asthma are those that induce airway inflammation with eosinophils (more common) or neutrophils along with airway hyperresponsiveness (AHR). The most common of these (indeed the most common cause of asthma) are IgE-mediated inhalant allergen exposures.
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