calotropis/edema

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Anti-inflammatory effect of the latex from Calotropis procera in three different experimental models: peritonitis, paw edema and hemorrhagic cystitis.

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Latex from Calotropis procera is widely used in folk medicine as a rich source of biologically active compounds capable of promoting diverse benefits such as control of dermal fungal infections, antimicrobial activities and pain relief among other useful properties. The aim of this work was to

Protective effect of proteins derived from the latex of Calotropis procera against inflammatory hyperalgesia in monoarthritic rats.

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Calotropis procera (family: Apocynaceae) is a plant growing in the wild and has been used in the traditional medicinal system for the treatment of various diseases. The plant produces milky latex that possesses potent antiinflammatory and analgesic properties. In present study the non-dialysable

Protective Effect of High Molecular Weight Protein Sub-fraction of Calotropis procera Latex in Monoarthritic Rats.

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BACKGROUND Proteins present in the latex of Calotropis procera have been shown to produce anti-inflammatory effect and to afford protection in various disease models. OBJECTIVE To determine the efficacy of high molecular weight protein sub-fraction (LPPI) of latex of C. procera in ameliorating joint

Proteins derived from in vitro culture of the callus and roots of Calotropis procera ameliorate acute inflammation in the rat paw.

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The callus and roots developed from the hypocotyl and cotyledon explants of the germinating seeds of Calotropis procera were grown in culture, and the proteins isolated from them (CP and RP) were evaluated for their efficacy in inhibiting edema formation induced by sub-plantar injection of

Calotropis procera latex-induced inflammatory hyperalgesia--effect of antiinflammatory drugs.

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The milky white latex of plant Calotropis procera produces inflammation of the skin and mucous membranes on accidental exposure. It produces edema on local administration due to the release of histamine and prostaglandins and is associated with hyperalgesia. In the present study we have evaluated

Inhibition of Calotropis procera latex-induced inflammatory hyperalgesia by oxytocin and melatonin.

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The latex of the wild growing plant Calotropis procera produces inflammation of the skin and mucous membranes upon accidental exposure. On local administration it elicits an intense inflammatory response due to the release of histamine and prostaglandins that is associated with hyperalgesia. In the

Antiedematogenic and antioxidant properties of high molecular weight protein sub-fraction of Calotropis procera latex in rat.

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OBJECTIVE The aim was to evaluate the effect of high molecular weight protein fraction of Calotropis procera latex on edema formation and oxidative stress in carrageenan-induced paw inflammation. METHODS A sub-plantar injection of carrageenan was given to induce edema in the hind paw of the rat. The

Calotropis procera (ushaar) keratitis.

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OBJECTIVE To report a case of permanent endothelial cell injury after intracorneal penetration of milky latex from Calotropis procera (ushaar). METHODS Interventional case report. METHODS A 40-year-old patient developed painless corneal edema despite minimal epithelial injury after exposure to

Corneal endothelial cytotoxicity of the Calotropis procera (ushaar) plant.

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OBJECTIVE To report 6 eyes of 5 patients with transient corneal edema after exposure to the milky latex of Calotropis procera (ushaar). METHODS Interventional case series. RESULTS Intracorneal penetration of ushaar latex can lead to permanent endothelial cell loss with morphologic alteration.

Calotropis procera -induced keratitis.

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Calotropis procera produces copious amounts of latex, which has been shown to possess several pharmacological properities. Its local application produces intense inflammatory response. In the 10 cases of Calotropis procera -induced keratitis reported here, the clinical picture showed corneal edema

Histamine mediates the pro-inflammatory effect of latex of Calotropis procera in rats.

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BACKGROUND Calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. However, the precise mode of its pro-inflammatory effect is not known. In present study we have pharmacologically characterized the inflammation

Ocular toxicity by latex of Calotropis procera (Sodom apple).

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We report the spectrum of ocular toxicity following accidental inoculation of latex of Calotropis procera (Sodom apple) in 29 eyes between January 2003 and December 2006. All patients presented with sudden painless dimness of vision with photophobia. Twenty-five (86%) patients had initial visual

Corneal Toxicity after Self-Application of Calotropis procera (Ushaar) Latex: Case Report and Analysis of the Active Components.

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Calotropis procera (ushaar) produces a copious amount of latex, which has both inflammatory and anti-inflammatory pharmacological properties. Local application produces an intense inflammatory response and causes significant ocular morbidity. We report corneal toxicity following

Clinical and pathological effects of Calotropis procera exposure in sheep and rats.

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This study aimed to describe the toxic effects resulting from the administration of Calotropis procera (Aiton) W. T. Aiton latex to rats and C. procera leaves to sheep. We studied male sheep that received C. procera leaves by gavage. Twenty male rats were separated into 5 groups and were subjected

Traditional medicine in oman: its role in ophthalmology.

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OBJECTIVE To present three patients with ocular disease who developed a range of complications following use of traditional medications. METHODS Case series METHODS Three patients who were examined in the Ophthalmic department of a tertiary care teaching hospital in the Sultanate of Oman between

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