cannabidivarin/neurodegenerative diseases

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Cannabis sativa: much more beyond Δ9-tetrahydrocannabinol.

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Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion, being regulated in several countries. However, the psychotropic effects of Δ⁹-tetrahydrocannabinol (THC), the main psychoactive compound of Cannabis sativa, are of concern. Thus, the interest in

Differences in receptor binding affinity of several phytocannabinoids do not explain their effects on neural cell cultures.

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Phytocannabinoids are potential candidates for neurodegenerative disease treatment. Nonetheless, the exact mode of action of major phytocannabinoids has to be elucidated, but both, receptor and non-receptor mediated effects are discussed. Focusing on the often presumed

A Systematic Review of Minor Phytocannabinoids with Promising Neuroprotective Potential

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Embase and Pubmed were systematically searched for articles addressing the neuroprotective properties of phytocannabinoids, aside from cannabidiol and Δ⁹ -tetrahydrocannabinol, including Δ⁹ -tetrahydrocannabinolic acid (Δ⁹ -THCA), Δ⁹

Phytocannabinoids as novel therapeutic agents in CNS disorders.

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The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has been used for thousands of years for both recreational and medicinal purposes. In the past two decades, characterisation of the body's endogenous cannabinoid (CB) (endocannabinoid, eCB) system (ECS) has highlighted

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