carapichea/chemotherapy

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Effect of zatosetron on ipecac-induced emesis in dogs and healthy men.

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Serotonin receptor (5-HT3) antagonists provide effective antiemetic therapy in cancer patients receiving emetogenic chemotherapy, such as cisplatin. Animal studies have shown that 5-HT3 receptor antagonists also have antiemetic activity in ipecac-induced emesis. The authors investigated the

Anticancer and reversing multidrug resistance activities of natural isoquinoline alkaloids and their structure-activity relationship.

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The severe anticancer situation as well as the emergence of multidrug-resistant (MDR) cancer cells has created an urgent need for the development of novel anticancer drugs with different mechanisms of action. A large number of natural alkaloids, such as paclitaxel, vinblastine and camptothecin have

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