carapichea/vomiting

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Effect of zatosetron on ipecac-induced emesis in dogs and healthy men.

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Serotonin receptor (5-HT3) antagonists provide effective antiemetic therapy in cancer patients receiving emetogenic chemotherapy, such as cisplatin. Animal studies have shown that 5-HT3 receptor antagonists also have antiemetic activity in ipecac-induced emesis. The authors investigated the

Rapid emesis from high-dose ipecac syrup in adults and children intoxicated with antiemetics or other drugs.

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The effect of ipecac syrup as an emetic in adults as well as children who had ingested antiemetics or other drugs was evaluated. Adults or children over five years of age were given 30 ml of ipecac syrup followed by 360 ml of water; children aged one to five years were given 15 ml ipecac syrup

Acupressure for prevention of emesis in patients receiving activated charcoal.

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OBJECTIVE Vomiting after activated charcoal decontamination is problematic. Acupressure (traditional Chinese medicine) is an effective treatment for emesis, but has not been tested in overdose patients. We sought to determine (1) the incidence of emesis after activated charcoal and (2) the ability

Comparative efficacy of maropitant and selected drugs in preventing emesis induced by centrally or peripherally acting emetogens in dogs.

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Maropitant (Cerenia; a novel, selective neurokinin(1) receptor antagonist), chlorpromazine, metoclopramide and ondansetron were compared in two randomized, placebo-controlled studies for efficacy in preventing emesis induced by emetogens acting centrally (apomorphine; Study 1) or peripherally (syrup

The effect of carbonated beverages on ipecac-induced emesis.

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To determine the effect of carbonated beverages on syrup of ipecac, 24 pediatric patients were randomly administered six ounces of water or a carbonated beverage with syrup of ipecac. Changes in the abdominal girth, the volume of emesis, and time of emesis were monitored in all patients. In the

Evaluation of gastric emptying using radionuclides: gastric lavage versus ipecac-induced emesis.

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OBJECTIVE To compare the efficacy of gastric lavage and ipecac-induced emesis by using a radionuclide marker in a simulated overdose and to determine the amount of material recoverable after lavage fluid appears clear. METHODS Case-control, prospective cross-over study. METHODS Nuclear medicine

Ipecac-induced emesis and gastric lavage are equally unpleasant.

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It has been widely held that gastric lavage is more unpleasant than ipecac-induced emesis. In fact, patients are occasionally threatened with large rubber tubes in order to persuade them to drink ipecac. To confirm that this assumption exists, we asked 41 emergency physicians and nurses who had

Mallory-Weiss syndrome: an unusual complication of ipecac-induced emesis.

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A young presented to the emergency department after ingesting multiple drugs. Upper gastrointestinal bleeding developed after emesis was induced with syrup of ipecac. A small Mallory-Weiss tear of the cardioesophageal junction was found at endoscopy. This case is presented to alert physicians to

Vomiting induction by ipecac syrup in dogs and ferrets.

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The dog has been used as an experimental animal in emesis research. In this study, we analyzed the emetic effects of ipecac syrup using a smaller animal, the ferret, and compared its response to that of the dog. Dogs and ferrets were divided into 4 groups (n = 4, each). Each group was given either

The effect of milk on ipecac-induced emesis.

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A prospective study at two regional poison centers was undertaken in 500 children under six years of age (mean age 2.3 y) to resolve the question of whether milk has an effect on ipecac-induced emesis. When home administration of ipecac was recommended, parents were asked to select either milk or

Recurrent infantile vomiting due to intentional ipecac poisoning.

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Recurrent vomiting is a common symptom in infancy that, when severe, may prompt an extensive diagnostic evaluation. We report a 1-year-old infant whose recurrent vomiting eluded diagnosis until ipecac syrup was detected in vomitus and urine. Separation of the infant from the mother resulted in

Ipecac-induced emesis and reduction of plasma concentrations of drugs following accidental overdose in children.

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Syrup of ipecac is widely used following accidental drug overdosage in children. Proof of its efficacy, however, in reducing the risk of poisoning is limited. We prospectively studied the effect of early v late induction of emesis by ipecac in 50 children younger than 5 years of age with accidental

The effect of fluid volume on syrup of ipecac emesis time.

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Large volumes of fluid have been recommended to aid rapid ipecac-induced emesis, however, large volume intake may also have deleterious effects. We prospectively studied 121 children treated at home by a regional poison center to determine if a relationship existed between fluid volume and time to

Pharmacological aspects of ipecac syrup (TJN-119)-induced emesis in ferrets.

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In order to elucidate the precise mechanism of ipecac syrup (TJN-119) on the occurrence of vomiting, we examined the effects of ipecac syrup on the abdominal afferent nerve activity as well as on the 5-HT levels of the ileum and area postrema in ferrets. Oral administration of TJN-119 (0.5 mg/kg)

The effect of temperature of concurrently administered fluid on the onset of ipecac-induced emesis.

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The time of onset of ipecac-induced emesis is not significantly influenced by the temperature of concurrently administered fluid. The average time of emesis with syrup of ipecac administered with cold (10 degrees C) versus warm (40 degrees C) water was found to be 30:59 and 30:18 min, respectively.

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