CROSS REFERENCE TO RELATED APPLICATIONS
The present application is a 35 U.S.C. .sctn.371 national stage entry of PCT/EP2012/004107, which has an international filing date of Oct. 1, 2012, and claims priority to German Patent Application No. 102011114528.5, filed on Sep. 29, 2011, contents of each of
The subject of the present invention is compounds which are antagonists of the cannabinoid CB.sub.2 receptors, their preparation, pharmaceutical compositions containing them. The compounds of the invention are tricyclic derivatives of 1-benzylpyrazole-3-carboxylic acid.
Patent applications EP-A-576
FIELD OF THE INVENTION
The present invention is generally directed to novel compositions and methods for treatment of dermatologic conditions. More particularly, a composition comprising Terpene and cannabidiol (CBD) or derivatives thereof for treating inflammatory skin disorders. Further, the
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not applicable.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The field of the present invention relates to the detection of controlled substances, and in particular to the detection of a metabolite of
CROSS-REFERENCE TO RELATED APPLICATIONS
Not Applicable.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not applicable.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The field of the present invention relates to the detection of controlled substances, and in particular to the
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not applicable.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The field of the present invention relates to the detection of controlled substances, and in particular to the detection of a metabolite of
CROSS REFERENCE TO RELATED APPLICATION
This application is a national stage of PCT/EP01/11967 filed Oct. 16, 2001 and based upon DE 100 51 427.8 filed Oct. 17, 2000 under the International Convention.
BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to a process for
FIELD OF THE INVENTION
The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclop- ropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that
FIELD OF THE INVENTION
The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclop- ropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that
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