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cardiomyopathies/obesity

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Suloexide in the Treatment of Early Stages of COVID-19

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Objective: To use sulodexide in patients that have early onset of COVID-19 symptoms to mitigate the progression of the disease process that can allow them to recover at home, and limit the need for hospital care and the more severe manifestation which includes fulminant respiratory failure, acute

Sarilumab for Patients With Moderate COVID-19 Disease

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1. Aims/Objectives The effectiveness of blockade of IL-6R in treating patients with COVID-19 disease of moderate severity will be tested in a pragmatic and adaptive randomized trial. The primary outcome is intubation or death within 14 days of enrollment OR administration of a rescue dose of IL-6

Value of SGLT2 Inhibitor (Dapagliflozin) as an Added Therapy in Diabetic Patients With Heart Failure With Reduced Ejection Fraction; Randomized Controlled Clinical Trial

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Primary Objective: The purpose of this study was to investigate the effect of Dapagliflozin, an inhibitor of sodium-glucose cotransporter 2, on cardiovascular Cardiomyopathy, morbidity and mortality in patients with type 2 diabetes. Secondary Objective: Change in the fibrosis and oxidative stress

Effect of Intraoperative Magnesium Infusion on Postoperative Pain and Cognitive Function

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This study will be conducted at Beni-Suef University Hospital after approval of the anesthesiology, surgical ICU and pain management department, and the local ethics and research committee, and obtaining written informed consents from the patients . The inclusion criteria: 1. Male and female

The Effects of SGLTi on Diabetic Cardiomyopathy

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Diabetic cardiomyopathy is defined as ventricular dysfunction in diabetic patients in the absence of coronary artery disease and hypertension. It is considered as a cardiac muscle disorder due to the metabolic consequences of DM characterized by left ventricular hypertrophy, left ventricular

Catheter Ablation vs. Risk Factor Modification.

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INTRODUCTION Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, having a prevalence of about ~ 2% in the general population. Among healthy men and women age 40 years, the risk of lifelong AF occurrence is approximately 25%. The current estimated prevalence of AF is

Clinical Efficacy of Telmisartan in Reducing Cardiac Remodeling Among Obese Patients With Hypertension

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At present, there are no guidelines for the treatment of obese patients with hypertension. Blood pressure control and effective control of obesity are important therapeutic targets for obesity-associated hypertension. Whether telmisartan can be used as PPAR-γ agonist, unlike other AT-1 receptor

Do Obese Patients With Primary Knee Osteoarthritis Benefit From a Single Bout of Moderate Intensity Aerobic Exercise?

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Study population: This is an observational study a cohort of sedentary Egyptian patients included thirty four obese patients role diagnosed with primary human knee joint OA according to the criteria of the American College of Rheumatology (ACR)( 8).were selected from those attending the outpatient

Electrophysiological Phenotyping Of Patients at Risk of Ventricular Arrhythmia and Sudden Cardiac Death

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Sudden cardiac death (SCD) occurs in groups that are neither traditionally considered high-risk nor have been the subject of large-scale studies. These include obesity, inflammatory arthropathy and gene-specific cardiomyopathy. Existing data to explain higher risk of arrhythmia in these cohorts rely

Esophageal Damage Protection During Pulmonary Vein Ablation. Pilot Study.

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1. THEORETICAL FRAMEWORK. APPROACH TO THE PROBLEM Background and justification Atrial fibrillation is the most common type of heart arrhythmia. Electrical isolation of the pulmonary veins in the left atrium with ablation is standard therapy in the invasive treatment of atrial fibrillation. One of

Serum Androgen Levels as a Marker for the Severity of Preeclampsia

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hypertensive disorders are one of the most important complications during pregnancy, which in combination with hemorrhage and infections make a dangerous triad, making them the major cause of maternal morbidity and mortality in 3.7-5% of all pregnancies. Hypertensive disorders during pregnancy are

The MHERO Study (Michigan's Hypertension, Diabetes, and Obesity Education Research Online)

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Adults with overweight or obesity, hypertension, and prediabetes or type 2 diabetes are at a high risk of adverse health outcomes including stroke, renal disease, myocardial infarction, and premature death. Evidence suggests that the first-line treatment for adults with this triple burden should be

Cardiac Magnetic Resonance in Non Ischemic Cardiomyopathy

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Nonischemic cardiomyopathy is considered as a variety of structural and functional myocardial disorders in which the myocardium is abnormal in the absence of diseases such as hypertension and coronary artery, valvular, and congenital heart diseases. Classification of cardiomyopathies is complex,

Inflammatory Axis and Sirtuins' in Overweight Pre-diabetics Patients

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In obese patients the visceral fat, and the superficial adipose tissue work as an endocrine active tissue to express different cytokines, and multiple molecular pathways implied in the cross talking with different part of the human body, such as the cardiovascular system. To date, adipocytes, and

Resistance Training and Cardiometabolic Health

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While it has been firmly established that aerobic exercise training is an effective modality for managing cardiometabolic disease risk, the influence of resistance training (RT) is not as well characterized. It is well established that RT improves muscular strength, size, cross sectional area, and
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