carica/antifungal

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Characterisation of general proteolytic, milk clotting and antifungal activity of Ficus carica latex during fruit ripening.

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BACKGROUND The physiological role of fig latex is to protect the plant from pathogens. Latex is a rich source of proteases, predominantly ficin. Fig latex also contains collagenolytic protease and chitinolytic enzymes. Our aim was to investigate changes in protein composition, enzyme and antifungal

Chemical composition and antifungal activity of Carica papaya Linn. seed essential oil against Candida spp.

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In recent years, the incidence of clinical yeast infections has increased dramatically. Due to the extensive use of broad-spectrum antifungal agents, there has been a notable increase in drug resistance among infections yeast species. As one of the most popular natural antimicrobial agents,

Antifungal action of Carica papaya latex: isolation of fungal cell wall hydrolysing enzymes.

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Carica papaya latex inhibits the growth of Candida albicans. Latex proteins appear to be responsible for this antifungal effect. The minimum protein concentration for producing a complete inhibition was estimated to be about 138 micrograms ml-1. Exploration of different glycosidic activities shows

Phytochemical and antifungal profiles of the seeds of carica papaya L.

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Phytochemical investigation of the ethanolic extracts of the seeds of Carica papaya L. (Caricaceae) led to the isolation of 2,3,4-trihydroxytoluene (caricaphenyl triol) and glyceryl-1-(2',3',4'-trihydroxybenzoyl)-2,3-dioleate (papayaglyceride) as the new phytoconstituents along with the known

Therapeutic application of Carica papaya leaf extract in the management of human diseases.

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Papaya (Carica papaya Linn.) belongs to the family Caricaceae and is well known for its therapeutic and nutritional properties all over the world. The different parts of the papaya plant have been used since ancient times for its therapeutic applications. Herein, we aimed to review the

Antifungal Activity in Ethanolic Extracts of Carica papaya L. cv. Maradol Leaves and Seeds.

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Bioactive compounds from vegetal sources are a potential source of natural antifungic. An ethanol extraction was used to obtain bioactive compounds from Carica papaya L. cv. Maradol leaves and seeds of discarded ripe and unripe fruit. Both, extraction time and the papaya tissue flour:organic solvent

Biological activities of Ficus carica latex for potential therapeutics in Human Papillomavirus (HPV) related cervical cancers.

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Infection caused by high-risk human papillomaviruses (HPVs) are implicated in the aetiology of cervical cancer. Although current methods of treatment for cervical cancer can ablate lesions, preventing metastatic disseminations and excessive tissue injuries still remains a major concern. Hence,

Fungicidal activity of latex sap from Carica papaya and antifungal effect of D(+)-glucosamine on Candida albicans growth.

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Carica papaya latex sap inhibits the growth of Candida albicans when added to a culture during the exponential growth phase. Approximately 60% was achieved. This fungistatic effect is the result of cell wall degradation due to a lack of polysaccharidic constituents in the outermost layers of the

Gene cloning and characterization of a novel recombinant antifungal chitinase from papaya (Carica papaya).

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A chitinase cDNA clone (CpCHI, 1002 bp) was isolated from papaya fruit, which encoded a 275 amino acid protein containing a 28 amino acid signal peptide in the N-terminal end. The predicted molecular mass of the mature protein was 26.2 kDa, and its pI value was 6.32. On the basis of its amino acid

In vitro erythrocyte membrane stabilization properties of Carica papaya L. leaf extracts.

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BACKGROUND Carica papaya L. fruit juice and leaf extracts are known to have many beneficial medical properties. Recent reports have claimed possible beneficial effects of C. papaya L. leaf juice in treating patients with dengue viral infections. This study aims to evaluate the membrane stabilization

Carica papaya leaves and cancer prevention: An overview

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Carica papaya is an essential medicinal plant having anticancer activities through diverse mechanisms and is not so far thoroughly investigated. In this review, we have summarized the systematic research outputs of different parts of the papaya plant extracts and elaborated the role of its

Isolation of two plant proteinases in latex from Carica candamarcensis acting as mitogens for mammalian cells.

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In a prior study we showed evidence that latex from Carica candamarcensis contains a protein fraction that stimulates mammalian cell proliferation. In this report we describe the isolation of two proteinases responsible for this effect. Both proteinases (P1, P2) display a relative mass of 23 kDa and

A synergistic effect of Carica papaya latex sap and fluconazole on Candida albicans growth.

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A mixture of Carica papaya latex (0.41 mg protein ml-1) and fluconazole (2 micrograms ml-1) showed a synergistic action on the inhibition of Candida albicans growth. Thus, with this mixture an equivalent inhibition rate was observed to that obtained when C. albicans was cultured in a medium

Carica papaya increases regulatory T cells and reduces IFN-γ+ CD4+ T cells in healthy human subjects.

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Fruit and vegetables have therapeutic potential as they dampen inflammation, have no known side-effects and as whole foods have prospective additive and synergistic benefits. Th1 (IFN-γ(+) CD4(+))/Th2 (IL-4(+)CD4(+)) T cells play a vital role in mediating inflammatory responses and may be regulated

Phytochemical screening and bioactivity assessment of leaves and fruits extract of Carica papaya.

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The consumption of fruits and vegetables has increased in recent years due to their health benefits as fruits and vegetables contain secondary metabolites, those has been reported to possess different pharmacological effects against many human ailments. In the current study antioxidants,

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