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cascabela thevetia/antifungal

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Diurnal variation in probability of death following self-poisoning in Sri Lanka--evidence for chronotoxicity in humans.

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BACKGROUND The absorption, distribution, metabolism and elimination of medicines are partly controlled by transporters and enzymes with diurnal variation in expression. Dose timing may be important for maximizing therapeutic and minimizing adverse effects. However, outcome data for such an effect in
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