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casimiroa calderoniae/non-alcoholic fatty liver disease

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[Pharmacodynamics of alcoholic and aqueous extracts from the Casimiroa edulis seed].

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The hypnotic properties of leaves and seed of Casimiroa edulis (zapote blanco) a tropical fruit, are well known. In the present investigation, pharmacological studies on aqueous and alcoholic extracts were carried out in dogs, cats, rabbits and guinea pigs, using different experimental models. The

Isolation of a hypotensive substance from seeds of Casimiroa edulis.

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The hypotensive activity of the alcoholic and aqueous extracts of C. edulis has been previously reported. The present paper describes the pharmacological studies of a substance isolated from the alcoholic extract. Preliminary chemical and pharmacological data allowed a histamine-like compound to be

Pharmacology of Casimiroa edulis; Part I. Blood pressure and heart rate effects in the anesthetized rat.

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The effect of an alcoholic extract of seeds of Casimiroa edulis on blood pressure and heart rate was determined in rats anesthetized with pentobarbital and compared with that of histamine. The extract induced hypotension, accompanied at high doses by tachycardia. Hypotension after histamine was more
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