catechol/breast neoplasms

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Exploring Compensation to Maintain Cognitive Function in Adults Newly Diagnosed With Brain Cancer

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Cognitive impairments experienced by cancer survivors, from time of diagnosis through the health trajectory, are distressing, persistent, and negatively impact everyday function and quality of life. While reports of cancer- and treatment-related cognitive concerns vary substantially and may be

Electroacupuncture Therapy in Reducing Chronic Pain in Patients After Breast Cancer Treatment

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PRIMARY OBJECTIVE: I. Determine the initial efficacy of electroacupuncture (EA) in reducing chronic pain in women following treatment for breast cancer. SECONDARY OBJECTIVES: I. Determine if EA produces greater improvement in physical functional mobility as compared to sham electroacupuncture (SEA)

A Prospective Pilot Study to Evaluate the Effect of Systemic Adjuvant Therapy on the Cognitive and Brain Function of Breast Cancer Patients

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Breast cancer is the most common cancer amongst women worldwide, with a lifetime risk of 7-8% in women and incidence rates ranging from 19.3-89.7 per 100,000 women in developing and developed countries. More than 1,383,500 cases of invasive breast cancer are estimated to be diagnosed worldwide,and

Studying Biomarkers in Nipple Fluid, Urine, and Blood Samples From Women With Newly Diagnosed Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer and in Women at Risk of Developing Breast Cancer

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OBJECTIVES: - To determine the levels of catechol estrogens (CE), CE metabolites, CE-DNA adducts, and CE conjugates in nipple aspirate fluid samples obtained from women with newly diagnosed ductal carcinoma in situ or stage I or II breast cancer and from women at high risk of developing breast

Defined Green Tea Catechin Extract in Treating Women With Hormone Receptor Negative Stage I-III Breast Cancer

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PRIMARY OBJECTIVES: I. Demonstrate the safety of green tea catechin extract (Polyphenon E) in women with a history of hormone receptor-negative breast cancer. II. Determine the maximum tolerated dose of Polyphenon E in women with a history of hormone receptor-negative breast cancer. SECONDARY

Catecholamine-O-Methyl-Transferase(COMT)-Polymorphism in Cardiac Surgery

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Aim of the study To explore if there is an impact of LL COMT genotype on clinical and biological outcome variables in patients undergoing cardiac surgery compared to HH genotype. Background Cardiac surgery has been shown to be an effective method for prolonging life in patients with severe coronary

Tamoxifen-MRI Study

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The project is a double blind, randomized, placebo-controlled phase II chemoprevention trial. The study outcomes will be biological markers, rather than cancer incidence or mortality. Eligible study subjects will be women, between the ages 25-45, whose calculated lifetime breast cancer risk is > 20%

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