celastrus/breast neoplasms

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Cytotoxic constituents from Celastrus paniculatus induce apoptosis and autophagy in breast cancer cells.

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Celastrus paniculatus is a traditional medicinal plant with diverse pharmacological activities. To identify its bioactive constituents, three new β-dihydroagarofuranoid sesquiterpenes were isolated from the whole plant, of which the major constituent is

Three novel sesquiterpene esters from Celastrus angulatus.

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Three new sesquiterpene polyol esters with a beta-dihydroagarofuran skeleton, NW12 (1), NW27 (2), and NW31 (4), together with a known compound, NW30 (3), were isolated from the root bark of Celastrus angulatus. Their chemical structures were elucidated by analyses of MS and NMR spectral data.

Elucidation of the Intestinal Absorption Mechanism of Celastrol Using the Caco-2 Cell Transwell Model.

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Celastrol, a triterpenoid isolated from stem (caulis) of Celastrus orbiculatus Thunb. (Celastraceae), has been known to have various pharmacological effects, including anti-inflammatory, anticancer, and antioxidant activities. However, the mechanism of the intestinal absorption of celastrol is

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