INTRODUCTION
This invention relates to a process for the production of a non-toxic B subunit of the heat-labile enterotoxin (LT-B) from a human isolate of an enterotoxigenic strain of Escherichia coli. This process utilizes recombinant DNA techniques, in which the requisite gene sequence is inserted
TECHNICAL FIELD
The present invention relates to an oral vaccine useful for preventing and treating a bacterial infectious disease, and a method for producing the same.
BACKGROUND ART
Typhoid fever is one of the infectious diseases caused by Salmonella enterica var. Typhi, which is a type of
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