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chronic pain/vomiting
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9 results
Benzoimidazole derivatives and pharmaceutical composition comprising the same
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TECHNICAL FIELD
The present invention relates, in general, to novel benzoimidazole derivatives and, more particularly, to novel benzoimidazole derivatives functioning as antagonists to a vanilloid receptor (capsaicin receptor; Transient Receptor Potential Channel, Vanilloid subfamily member 1;
Biaryl benzoimidazole derivatives and pharmaceutical composition comprising the same
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TECHNICAL FIELD
The present invention relates to a novel biaryl benzoimidazole derivative, a method for preparing the same, and a pharmaceutical composition comprising the same, in which the biaryl benzoimidazole derivative functions as an antagonist of the vanilloid receptor (Capsaicin receptor;
Benzimidazolone derivatives as CB2 receptor ligands
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BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone derivatives. These compounds have selective cannabinoid(CB)2 receptor binding activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the
Sulfonyl benzimidazole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to sulfonyl benzimidazole derivatives. These compounds have selective cannabinoid (CB)2 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives
2-phenylpiperazine derivatives
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FIELD OF THE INVENTION
The present invention relates to novel 2-phenylpiperazine derivatives and pharmaceutical compositions containing the derivatives as an effective component.
BACKGROUND OF THE INVENTION
Tachykinin is a general term for a group of peptides having similar structures. In mammals,
Transdermal buprenorphine dosage regimen for analgesia
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FIELD OF THE INVENTION
The present invention relates to effective dosage regimens for the treatment of chronic pain. The regimen includes administering to a patient a series of transdermal dosage forms including ascending dosages of buprenorphine. It specifically relates to treating pain in elderly
Carbamic acid derivatives
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BACKGROUND OF THE INVENTION
In the central nervous system (CNS) the transmission of stimuli takes place by the interaction of a neurotransmitter, which is sent out by a neuron, with a neuroreceptor.
L-glutamic acid, the most commonly occurring neurotransmitter in the CNS, plays a critical role in a
Carbamic acid derivatives
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BACKGROUND OF THE INVENTION
In the central nervous system (CNS) the transmission of stimuli takes place by the interaction of a neurotransmitter, which is sent out by a neuron, with a neuroreceptor.
L-glutamic acid, the most commonly occurring neurotransmitter in the CNS, plays a critical role in a
4,5 dihydro-(1H)-pyrazole derivatives as cannabinoid CB.sub.1 receptor modulators
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The present disclosure relates to the fields of pharmaceutical and organic chemistry, and provides 4,5-dihydro-(1H)-pyrazole (pyrazoline) derivatives as cannabinoid CB.sub.1 receptor modulators, intermediates for synthesizing these compounds, formulations comprising these compounds, methods for
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