chronic periodontitis/glutathione

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Polymorphisms in Glutathione S-Transferase M1, T1, and P1 in Patients with Chronic Periodontitis: A Pilot Study.

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Background. Although the direct cause of chronic periodontitis is bacterial infection, the progression of this disease depends on genetic and environmental factors, and smoking is a known risk factor in the development and severity of the disease. An individual's susceptibility may be influenced by

Effect of smokeless tobacco use on salivary glutathione levels among chronic periodontitis patients before and after non-surgical periodontal therapy

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Introduction: Smokeless tobacco (SLT) jeopardizes periodontal health and also produces an imbalance between reactive oxygen species (ROS) and antioxidants (AO) such as glutathione. Glutathione is an important redox regulator in saliva and

Evaluation of non-surgical therapy on glutathione levels in chronic periodontitis.

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OBJECTIVE To compare the levels of glutathione (GSH), both oxidized and reduced forms in patients with and without chronic periodontitis in gingival crevicular fluid (GCF). METHODS Twenty GCF samples from maxillary quadrants were collected using capillary micropipettes from the chronic periodontitis

Evaluation of glutathione level in gingival crevicular fluid in periodontal health, in chronic periodontitis and after nonsurgical periodontal therapy: A clinicobiochemical study.

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BACKGROUND Periodontitis is predominantly due to exaggerated host response to pathogenic microorganisms and their products which causes an imbalance between the reactive oxygen species-antioxidant in gingival crevicular fluid (GCF). Glutathione is an important redox regulator in GCF and maintenance

Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro.

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The production of high levels of reactive oxygen species by neutrophils is associated with the local and systemic destructive phenotype found in the chronic inflammatory disease periodontitis. In the present study, we investigated the ability of sulforaphane (SFN) to restore cellular glutathione

Oxidative stress-related biomarkers in saliva and gingival crevicular fluid associated with chronic periodontitis: A systematic review and meta-analysis.

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Oxidative stress (OS) biomarkers have been detected in saliva and gingival crevicular fluid (GCF) during chronic periodontitis (CP) progression; however, the relationship between OS biomarkers and CP progression remains elusive. The purpose of this meta-analysis is to investigate the

Effect of nonsurgical periodontal therapy on crevicular fluid and serum glutathione peroxidase levels.

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BACKGROUND Plasma glutathione peroxidase (eGPx) is an important selenium containing antioxidant in human defense against oxidative stress. While crevicular fluid (GCF) eGPx levels and its association with periodontal disease is well documented, there is no data on correlation of GCF and serum eGPx

Glutathione levels in plasma, saliva and gingival crevicular fluid after periodontal therapy in obese and normal weight individuals.

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OBJECTIVE The purpose of this study was to investigate the effects of obesity on reduced and oxidized glutathione (GSH and GSSG) levels in the gingival crevicular fluid, plasma and saliva of patients with chronic periodontitis and to evaluate the changes after nonsurgical periodontal

Influence of Periodontal Clinical Status on Salivary Levels of Glutathione Reductase.

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Inadequate antioxidant balance may play a role in the excessive tissue breakdown in periodontitis. Because aggressive periodontitis (AgP) not only differs from chronic periodontitis (CP) in terms of clinical manifestations, this study investigates whether the salivary levels of glutathione reductase

Effects of a self-ligating appliance for orthodontic treatment of severe adult periodontitis.

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This study was conducted to investigate the short-term effects of a self-ligating appliance for orthodontic treatment of severe adult periodontitis. Thirty patients diagnosed as severe periodontitis were recruited at Nanjing Stomatological Hospital, P. R.China, between January 2012 and January 2016.

Crevicular fluid glutathione levels in periodontitis and the effect of non-surgical therapy.

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OBJECTIVE To quantify reduced and oxidized glutathione (GSH and GSSG) levels in gingival crevicular fluid (GCF) of periodontitis patients pre-therapy (versus periodontally healthy controls) and ascertain whether successful non-surgical therapy alters glutathione levels. METHODS Thirty-second GCF

Quantitative gingival crevicular fluid proteome in type 2 diabetes mellitus and chronic periodontitis.

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OBJECTIVE The aim of this study was to investigate the proteome of the gingival crevicular fluid comparing the relative abundance of proteins from type 2 diabetes mellitus (2DM) individuals and chronic periodontitis (CP) affected sites, subjects affected by both conditions and healthy

Assessment of some biochemical oxidative stress markers in male smokers with chronic periodontitis.

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The present study aims to assess and compare the biochemical oxidative stress markers in male smokers and non-smokers with chronic periodontitis. One hundred thirty-four male chronic periodontitis patients and 64 apparently healthy male volunteers were recruited for the study. The periodontal status

[The relationship between GPx activity in gingival fluid and clinical parameters of adult periodontitis].

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OBJECTIVE To study the relationship of glutathione peroxidase (a natural FR scavenger) in gingival cervical fluid (GCF) of patients with periodontitis. METHODS GCF was collected from 44 sites of 23 patients with adult periodontitis. The volume of GCF was measured with Periotron 8000. GCF-GPx

Evaluation of the efficacy of taurine as an antioxidant in the management of patients with chronic periodontitis.

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BACKGROUND In the recent years, various studies have shown a link between the free radicals, antioxidants and periodontal diseases. The purpose of the present study was to evaluate the oxidative stress and the antioxidant status present in the gingival tissue and plasma of patients with chronic

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