clerodane diterpene/atrophy

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Antiulcer activity and subacute toxicity of trans-dehydrocrotonin from Croton cajucara.

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The antiulcerogenic activity of trans-dehydrocrotonin (DHC), a nor-clerodane diterpene isolated from Croton cajucara Benth. (Euphorbiaceae), and its subacute (35 days) toxicity were studied in mice and rats, respectively. For the antiulcerogenic tests, models of gastric ulcers induced in mice by

Two novel clerodane diterpenenes with NGF-potentiating activities from the twigs of Croton yanhuii.

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Nerve growth factor (NGF) and analog reagents to promote the neurite outgrowth of nerve cells against the neuron degeneration are expected to be potentially useful for the medical treatment of Alzheimer's disease. In our focus on the discovery of bioactive diterpenes, we investigated the chemical

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