Lycorine (1), one of the main alkaloids of the Amaryllidaceae family, was found to be responsible for the pronounced antiviral activity of the crude extracts from the roots and leaves of Clivia miniata Regel. It was shown that the inhibitory activity of lycorine on the cytopathogenic effect caused
OBJECTIVE
Determine a relationship between the neuroprotective activity and the antioxidant capacity of the Amaryllidaceae alkaloids in a model of Glu excitotoxicity in rat cortical neurons.
METHODS
Was evaluated several alkaloidal fractions isolated from Amaryllidaceae species, a family known to
Amaryllidaceae is a well-known family for its high alkaloidal content. These alkaloids comprise a unique group of bases that have been found to occur in this family. The Amaryllidaceae alkaloids represent a large and still expanding group of isoquinoline alkaloids, the majority of which are not
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