cocos nucifera/sarcoma

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Molecular mass and antitumor activities of sulfated derivatives of alpha-glucan from Poria cocos mycelia.

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Two kinds of water-insoluble (1-->3)-alpha-D-glucan samples, ab-PCM3-I and ac-PCM3-I, isolated from different Poria cocos mycelia were sulfated, to produce two series of water-soluble derivatives ab-PCM3-I-S1-S5 and ac-PCM3-I-S1-S5, respectively. The derivatives having different weight-average

Correlation of structure to antitumor activities of five derivatives of a beta-glucan from Poria cocos sclerotium.

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A water-insoluble (1-->3)-beta-D-glucan isolated from fresh sclerotium of Poria cocos was, respectively, sulfated, carboxymethylated, methylated, hydroxyethylated, and hydroxypropylated, to afford five water-soluble derivatives. Their weight-average molecular masses (Mw) and intrinsic viscosities

Antitumor activities of heteropolysaccharides of Poria cocos mycelia from different strains and culture media.

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Ten water-soluble heteropolysaccharide fractions were isolated from Poria cocos mycelia cultured from one wild and one cultivated strain in two identical culture media differing only in one component: either corn steep liquor or bran extract. The chemical compositions, including monosaccharide

Immunopotentiation and anti-tumor activity of carboxymethylated-sulfated beta-(1-->3)-d-glucan from Poria cocos.

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A carboxymethylated-sulfated derivative of (1-->3)-beta-d-glucan (PCS3-II) extracted from Poria cocos was synthesized and coded as CS-PCS3-II. Results of infrared (IR) and Carbon-13 nuclear magnetic resonance spectroscopy ((13)C NMR) indicated that CS-PCS3-II contained carboxymethyl and sulfate

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