codeine/dental caries

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Pain Intensity During Ultrasound Assessment of Uterine Cavity and Tubal Patency With and Without Painkillers: Prospective Observational Study.

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To determine the pain intensity and incidence of mild to severe pain during the ultrasound assessment of the uterine cavity and tubal patency using saline, air and saline, and foam as contrasts with and without painkiller. Prospective observational study (Canadian Task Force classification

No effect of preoperative paracetamol and codeine suppositories for pain after termination of pregnancies in general anaesthesia.

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Outpatient surgery demands rapid recovery and satisfied patients. The purpose of the study was to investigate whether rectal premedication with paracetamol and codeine would reduce the need of rescue analgesics, reduce the postoperative pain experience and result in faster eligibility for discharge.

Correlation of saliva codeine concentrations with plasma concentrations after oral codeine administration.

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A clinical study was designed to determine if there was a predictable relationship between saliva and plasma codeine concentrations. Drug-free volunteers (n = 17) were administered a 30-mg dose of liquid codeine phosphate. Plasma and saliva specimens were collected at various times for 24 h after

Codeine did not increase analgesic efficacy of coxibs in contrast to that of paracetamol or ibuprofen: isobolographic analysis in mice.

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OBJECTIVE There is good evidence that opioids can potentiate analgesic activity of some older non-opioid analgesics (such as paracetamol or ibuprofen) but it is not known whether this also holds true for newer non-opioid analgesics that selectively inhibit cyclooxygenase 2 (coxibs). This study was

Two techniques to sample non-volatiles in breath-exemplified by methadone.

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The particles in exhaled breath provide a promising matrix for the monitoring of pathological processes in the airways, and also allow exposure to exogenous compounds to be to assessed. The collection is easy to perform and is non-invasive. The aim of the present study is to assess if an exogenous

Oral fluid collection: the neglected variable in oral fluid testing.

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The potential to use oral fluid as a drug-testing specimen has been the subject of considerable scientific interest. The ease with which specimens can be collected and the potential for oral fluid (OF) drug concentrations to reflect blood-drug concentrations make it a potentially valuable specimen

Long-term outcome of radiofrequency ablation for intraoral microcystic lymphatic malformation.

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OBJECTIVE To determine long-term outcome of radiofrequency (RF) ablation of microcystic lymphatic malformation (LM) of the oral cavity for control of recurrent infection and bleeding. METHODS Institutional review board-approved retrospective study, METHODS Tertiary pediatric medical

Surgical treatment of jaw osteonecrosis in "Krokodil" drug addicted patients.

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Retrospective study of jaw osteonecrosis treatment in patients using the "Krokodil" drug from 2009 to 2013. On the territory of the former USSR countries there is widespread use of a self-produced drug called "Krokodil". Codeine containing analgesics ("Sedalgin", "Pentalgin" etc), red phosphorus

THE ACTION OF DRUGS ON RESPIRATION : I. THE MORPHINE SERIES.

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1. A method is described for recording intrathoracic pressure in cats without opening the pleural cavity; active expiratory movements were elicited by inhalation of a constant CO(2)-air mixture for a given time and a study was made of the action of drugs on inspiration and expiration. 2. Morphine

Determination of drugs of abuse in bovine dentin using liquid chromatography-electrospray ionization tandem mass spectrometry.

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Drugs deposited in human teeth are well preserved; the spectrum of toxicological investigations may therefore be supplemented by an analysis method for drugs in teeth. A liquid chromatography-electrospray ionization tandem mass spectrometry assay for the detection and quantification of basic drugs

Determination of heroin metabolites in human urine using capillary zone electrophoresis with beta-cyclodextrin and UV detection.

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A method has been developed for the detection of a mixture of morphine, codeine, 6-acetyl morphine (6-AM) and normorphine using capillary zone electrophoresis (CZE). The method utilized urinary 6-AM as a diagnostic indicator of heroin abuse because it is not a product of either morphine or codeine

Ibuprofen in the treatment of children's inflammatory pain: a clinical and pharmacological overview.

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Unlike fever, which is often over-treated especially in children, pain is underestimated and under-treated in pediatric age. The pharmacological agents approved for treating pain in these patients are few, also considering the recent limitation for codeine in children younger than 12 years.

Ibuprofen for Pain Control in Children: New Value for an Old Molecule.

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BACKGROUND Acute pain is one of the major complaints reported in pediatric emergency departments and general wards. Recently, both the US Food and Drug Administration and European Medicine Agency emitted some warnings regarding the use of opioids, including codeine, in children. OBJECTIVE The aims

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