codeine/seizures

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Toxicological Screening by GC-MS Among Children Admitted for a First Afebrile Seizure

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Before the age of 14 years, 1% of the paediatric population will develop a seizure. The only systematically required complementary examination is an electroencephalogram (EEG). Additional biological or radiological examinations depend on the circumstances, the past medical history of the patient and

Gabapentin for Pain Control After Osmotic Dilator Insertion and Prior to D&E Procedure: a Randomized Controlled Trial

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The investigators have planned a double-blind randomized controlled trial of repeated doses of gabapentin compared to placebo for pain management during the time after dilator insertion and prior to D&E the subsequent day. - Participants will receive gabapentin 600 mg or placebo prior to dilator

Postoperative Tramadol/Gabapentin/Ibuprofen Versus Tramadol/Placebo/Ibuprofen

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Hypotheses H1: Children who receive scheduled tramadol 1mg/kgQ6h with scheduled gabapentin (3 mg/kg/q6h dose) and PRN ibuprofen will experience better pain relief than children who receive scheduled tramadol 1mg/kgQ6h with PRN ibuprofen following tonsillectomy. H2: Children who receive scheduled

Bupivacaine, Levobupivacaine and Ropivacaine After Intrathecal and Extradural Injection in Labour

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Despite 40 years of epidural analgesia, a consensus still does not exist regarding the best local anesthetic or the best technique for the provision of pain relief in early labour. Two new local anesthetics, levobupivacaine and ropivacaine, have recently been introduced into clinical practice

IV Ibuprofen for Post-Electroconvulsive Therapy Myalgia

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IV ibuprofen (trade name Caldolor) is a novel therapeutic modality approved by the US Food and Drug Administration (FDA) in June 2009 for the treatment of mild to moderate pain, as an adjunct to opioid analgesics, and for the reduction of fever. Ibuprofen is a non-steroidal anti-inflammatory drug

Pharmacokinetics of Low Dose Ketamine Infusion

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Background: There has been an increasing awareness of the need for adequate sedation and analgesia in critically ill pediatric patients. The choices of treatment for pain are numerous, but in the Pediatric ICU parenteral opioids are most commonly used. At equipotent doses, all mu agonist opioids

Impact of Low Dose Naloxone on Fentanyl Requirements in Pediatric ICU Patients

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Objective: To determine if Naloxone administration to pediatric ICU patients on Fentanyl infusions require less Fentanyl compared to control patients. Background: During recent years there has been an increased awareness of the need for adequate sedation and analgesia of critically ill pediatric

Neuraxial Pethidine After Lumbar Surgery Trial

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Rationale Lumbar laminectomy is commonly performed to alleviate local or nerve root pain in the lower back and legs. Post-operative pain relief may consist of oral or parenteral medication, with an increasing body of research focussing on the use of epidural analgesics and anaesthetics (see

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