cone dystrophy/hypoxia

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Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia.

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Degeneration of cone photoreceptors leads to loss of vision in patients suffering from age-related macular degeneration (AMD) and other cone dystrophies. Evidence, such as choroidal ischemia and decreased choroidal blood flow, implicates reduced tissue oxygenation in AMD pathology and suggests a

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