OBJECTIVE
Transient congenital hypothyroidism (TCH) could disturb carbohydrate metabolism in adulthood. Aging is associated with increased risk of type 2 diabetes. This study aims to address effects of TCH on mRNA expressions of glucose transporters (GLUTs) and glucokinase (GcK) in islets and
In two cases of infantilism of the type of Herter, in one case of achondroplasia, and in one case of cretinism, creatin was constantly present in the urine and was increased in amount when the ingestion of carbohydrates was increased.
The authors report their experience in populational screenings, first regarding hyperphenylalaninemias at the city of S Paulo, by own programmation. In the same aminoacidopathies detection program, a similar methodology is being used in urine, in the children's health services of the State of S.
The brain is an organ elaborated and functioning from substances present in the diet. Dietary regulation of blood glucose level (via ingestion of food with a low glycemic index ensuring a low insulin level) improves the quality and duration of intellectual performance, if only because at rest the
BACKGROUND
Thyroxin (T(4)) plays an important role in the regulation of the rate of metabolism of proteins, fats, and carbohydrates. Congenital hypothyroidism, an inherited deficiency of thyroid hormones, is screened in newborns using a variety of methods that include total T(4) or thyroid
The uptake of D-3H-glucosamine by the developing cochlea of normal and hypothyroid rats was examined using light microscopic radioautography. During postnatal development, normal and hypothyroid rat cochleas exhibited a layer of radiolabelling in the tectorial membrane (TM). This layer first
Nutritional status during pregnancy can have a significant impact on maternal and neonatal health outcomes. Requirements for macronutrients such as energy and protein increase during pregnancy to maintain maternal homeostasis while supporting foetal growth. Energy restriction can limit gestational
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