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coptis trifolia/triacylglycerol

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ArticlesClinical trialsPatents
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Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.

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BACKGROUND Obesity is closely related to the metabolism of triacylglycerol (TG) in adipocytes. Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) are rate-limiting enzymes that control the hydrolysis of TG. Effects on ATGL and HSL to increase lipolysis may counteract obesity.

Chinese herbal extracts (SK0506) as a potential candidate for the therapy of the metabolic syndrome.

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The metabolic syndrome has reached epidemic proportions worldwide, but currently there is a lack of effective therapies for this multifactorial endocrine disease. TCM (traditional Chinese medicine) has been utilized to treat a wide variety of diseases for centuries in the People's Republic of China,
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