corneal perforation/arginine

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Nona-D-arginine amide for prophylaxis and treatment of experimental Pseudomonas aeruginosa keratitis.

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OBJECTIVE Nona-D-arginine amide (D9R) affected a cure of Pseudomonas aeruginosa corneal disease when combined with ciprofloxacin. In this study, we show that D9R alone and prophylactic treatment with D9R significantly reduced corneal pathology and bacterial burden associated with P. aeruginosa

Nona-D-arginine amide suppresses corneal cytokines in Pseudomonas aeruginosa keratitis.

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OBJECTIVE Nona-D-arginine (D9R) amide suppressed interleukin 1β production during Pseudomonas aeruginosa corneal infection. The purpose of this study was to determine the cellular disposition of D9R and its effect on other inflammatory mediators induced by infection. METHODS Mouse eyes received 5 μL

Nona-D-arginine therapy for Pseudomonas aeruginosa keratitis.

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OBJECTIVE Nona-D-arginine amide (D9R) was evaluated as treatment for Pseudomonas aeruginosa keratitis when administered alone and with ciprofloxacin. METHODS Mouse corneas were infected with P. aeruginosa. Immediately after infection and hourly for 5 hours, eyes received 5 microL of either Dulbecco

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