cotinine/seizures

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Intravenous and oral suicidal e-liquid poisonings with confirmed nicotine and cotinine concentrations.

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The increasing availability of e-cigarettes is a potential toxicological concern. E-cigarettes appeared on the Polish market in 2006, and since 2009 they have been widely available with a new source of nicotine, the so-called e-liquid. In this paper two cases of suicidal oral and intravenous

Cotinine antagonizes the behavioral effects of nicotine exposure in the planarian Girardia tigrina.

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Nicotine is one of the most addictive drugs abused by humans. Our laboratory and others have demonstrated that nicotine decreases motility and induces seizure-like behavior in planarians (pSLM, which are vigorous writhing and bending of the body) in a concentration-dependent manner. Nicotine also

The selectively bred high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats differ in sensitivity to nicotine.

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BACKGROUND Studies in rodents selectively bred to differ in alcohol sensitivity have suggested that nicotine and ethanol sensitivities may cosegregate during selective breeding. This suggests that ethanol and nicotine sensitivities may in part be genetically correlated. METHODS Male and female high

Self-poisoning among adults using multiple transdermal nicotine patches.

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OBJECTIVE To investigate the characteristics and outcomes of poisoning cases involving the dermal application of multiple transdermal nicotine patches. METHODS Case series; prospective postmarketing surveillance over a 24 month period. METHODS Telephone reports from 34 participating US poison

Maternal marijuana use, adverse pregnancy outcomes, and neonatal morbidity.

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The Eunice Kennedy Shriver National Institute of Child Health and Human Development Stillbirth Collaborative Research Network previously demonstrated an association between stillbirth and maternal marijuana use as defined by the presence of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid in

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