cystinuria/proline

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Amino acid imbalance in cystinuria.

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After oral ingestion of a free amino acid mixture by three cystinuric patients, plasma increments of lysine and arginine were lower and those of many other amino acids were significantly higher than those found in control subjects. Similar results were obtained in control subjects after amino acid

Molecular biology of mammalian amino acid transporters.

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Recently a number of alpha-amino acid transport proteins and corresponding cDNA clones have been isolated and categorized into gene families. The "CAT family" contains two members that mediate high-affinity Na(+)-independent transport of cationic amino acids in many tissues, and a third member that

Effect of cycloleucine on amino acid accumulation by human diploid fibroblasts.

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Cycloleucine is a synthetic amino acid which produces, in vivo, biochemical abnoramlities comparable to those seen in human cystinuria-lysinuria. The effect of cycloleucine on intracellular accumulation of amino acids overlapping separate transport systems was studied using human diploid fibroblasts

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