In bacterial and mammalian cells, N-(phosphonoacetyl)-L-aspartate (PALA) suppresses growth by strongly inhibiting aspartate transcarbamoylase (ATCase; EC 2.1.3.2), a key enzyme of the pyrimidine biosynthetic pathway. At a concentration that would suppress growth in mammalian or bacterial cells, and
Organic farming aims to be environmentally sound, but the question as to whether organic cropping brings more nutritional benefits to farmers and consumers than the conventional cropping needs still to be answered. To gain insights into the molecular effects of organic farming we used proteome
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