dermatomyositis/triglyceride

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Anti-lipoprotein lipase antibody in systemic sclerosis: association with elevated serum triglyceride concentrations.

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OBJECTIVE The vascular damage systemic sclerosis (SSc) consists mainly of microvascular changes, but recently macrovascular changes with dyslipidemia were recognized. In systemic lupus erythematosus (SLE), autoantibody to lipoprotein lipase (LPL), a key enzyme that hydrolyzes triglycerides,

Study of subcutaneous fat in children with juvenile dermatomyositis.

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OBJECTIVE Lipodystrophy is a recently recognized complication of juvenile dermatomyositis (juvenile DM). Until now, the diagnosis has been based only on the physical appearance of the patient. We quantified the patterns of fat distribution in a cohort of patients with juvenile DM. METHODS Twenty

Perimysial Microarteriopathy in Dermatomyositis with Anti-Nuclear Matrix Protein-2 Antibodies.

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Dermatomyositis (DM) with anti-nuclear matrix protein-2 (NXP-2) antibodies usually shows multifocal ischemic lesions in muscle. Here, we aimed to investigate the microarteriopathy underlying muscle ischemia in anti-NXP-2 positive DM METHODS: Sixteen patients diagnosed with anti-NXP-2

Juvenile dermatomyositis: is periodontal disease associated with dyslipidemia?

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Association between periodontal disease and dyslipidemia was recently reported in healthy adults. However, a systematic evaluation of concomitant periodontal diseases and lipid profile was not carried out in juvenile dermatomyositis (JDM). A cross-section study was performed in 25 JDM

Serum adipocytokine profile and metabolic syndrome in young adult female dermatomyositis patients.

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UNASSIGNED To analyse the frequency of metabolic syndrome in young adult female dermatomyositis patients and its possible association with clinical and laboratory dermatomyositis-related features and serum adipocytokines. UNASSIGNED This cross-sectional study included 35 dermatomyositis patients and

Polymyositis-dermatomyositis: diagnostic and prognostic significance of muscle alkaline phosphatase.

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The distribution and intensity of alkaline phosphatase deposition in 54 patients with dermatomyositis-polymyositis (PM-DM) was analyzed by the enzyme histochemical method. Increased enzyme reactivity of endomysial capillaries was found in 28% of patients, equally distributed between adult onset PM

Endothelial progenitor cell number is not decreased in 34 children with Juvenile Dermatomyositis: a pilot study.

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OBJECTIVE A pilot study to determine endothelial progenitor cells (EPC) number in children with Juvenile Dermatomyositis (JDM). METHODS After obtaining informed consent, the EPC number from 34 fasting children with definite/probable JDM at various stages of therapy-initially untreated, active

Clinical significance of subcutaneous fat and fascial involvement in juvenile dermatomyositis.

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OBJECTIVE Subcutaneous involvement, including calcinosis and panniculitis, is a more common complication in juvenile dermatomyositis (JDM) than in adult dermatomyositis. Magnetic resonance imaging (MRI) is useful for evaluating disease distribution. We investigated the clinical significance of

Traditional cardiovascular risk factors and coronary artery calcification in adults with polymyositis and dermatomyositis: a Danish multicenter study.

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OBJECTIVE To determine the occurrence of traditional cardiovascular (CV) risk factors and coronary artery calcification (CAC) in adults with polymyositis (PM) or dermatomyositis (DM) compared to healthy controls and to assess the association between CV risk factors, PM/DM, and CAC

Lipid profiles in untreated patients with dermatomyositis.

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OBJECTIVE Altered lipid levels may occur in autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis. However, serum lipid profiles in patients with dermatomyositis (DM) have not been investigated. Our aim was to identify lipid profiles in untreated DM patients, and to

Dyslipidaemia in juvenile dermatomyositis: the role of disease activity.

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OBJECTIVE To evaluate the presence of dyslipidaemia in JDM and its possible risk factors. METHODS Twenty-ﬁve JDM patients were compared to 25 healthy controls according to demographic data, body composition, fasting lipoproteins, glycaemia, insulin, antibodies and muscle enzymes. JDM scores were

AST/ALT ratio as a predictor of mortality and exacerbations of PM/DM-ILD in 1 year-a retrospective cohort study with 522 cases

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Objective: To assess the associations between aspartate transaminase/alanine transaminase ratio (DRR) and mortality in patients with polymyositis/dermatomyositis-associated interstitial lung disease (PM/DM-ILD).

[Fundamental examination and the reference values of anticardiolipin antibodies].
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We studied sera from 146 healthy individuals in a fundamental examination to obtain reference values for anticardiolipin antibodies by the enzyme-linked immunosorbent assay (ELISA). The good results were obtained in the evaluation of concentrations of pretreatment substances, cardiolipin antigen and

Lipid profile of pediatric patients with chronic rheumatic diseases - a retrospective analysis
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Aim: To describe the prevalence of dyslipidemia in children and adolescents with autoimmune rheumatic diseases (ARDs), particularly juvenile idiopathic arthritis (JIA), juvenile systemic lupus erythematosus (jSLE), and juvenile

[EARLY DETECTION OF ENDOTHELIAL DYSFUNCTION IN CHILDREN WITH AUTOIMMUNE DISEASES BY A NOVEL NONINVASIVE TECHNIQUE].
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Atherosclerosis is emerging as one of the most important causes of morbidity and mortality among patients with different rheumatologic disease. Endothelial dysfunction may be an early sign of atherosclerosis. To evaluate the occurrence of endothelial dysfunction in children with autoimmune diseases,

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