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desglucouzarin/asclepias
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5 results
Inhibition of Na+,K+-ATPase by the cardenolide 6'-O-(E-4-hydroxycinnamoyl) desglucouzarin.
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Among the major cardenolides from the milkweed Asclepias asperula, 6'-O-(E-4-hydroxycinnamoyl) desglucouzarin has not been characterized biochemically. In this study, its binding affinity for a physiological receptor, porcine kidney Na+,K+-ATPase, was found to be lower than the other cardenolides in
Uzarigenin and desglucouzarin from Asclepias syriaca L.
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Antiproliferative activity of cardenolide glycosides from Asclepias subulata.
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BACKGROUND
Asclepias subulata Decne. is a shrub occurring in Sonora-Arizona desert (Mexico-USA). The ethnic groups, Seris and Pimas, use this plant for the treatment of sore eyes, gastrointestinal disorders and cancer.
OBJECTIVE
To isolate the compounds responsible for antiproliferative activity of
Cytotoxicity of cardenolides and cardenolide glycosides from Asclepias curassavica.
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A new cardenolide, 12beta,14beta-dihydroxy-3beta,19-epoxy-3alpha-methoxy-5alpha-card-20(22)-enolide (6), and a new doubly linked cardenolide glycoside, 12beta-hydroxycalotropin (13), together with eleven known compounds, coroglaucigenin (1), 12beta-hydroxycoroglaucigenin (2), calotropagenin (3),
Apoptotic activities of cardenolide glycosides from Asclepias subulata.
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BACKGROUND
Asclepias subulata Decne. (Apocynaceae) is a shrub occurring in Sonora-Arizona desert. The ethnic groups of Sonora, Mexico, Seris and Pimas, use this plant for the treatment of sore eyes, gastrointestinal disorders and cancer.
OBJECTIVE
To determine the cell death pathways that the
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