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dihydroparthenolide/magnolia champaca

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Sesquiterpene lactones and other constituents from a cytotoxic extract of Michelia floribunda.

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The pentane and CHCl3 fractions of a crude extract of Michelia floribunda exhibited cytotoxic activity when tested in KB and P388 tumor cell cultures. Repeated chromatography led to the isolation of three cytotoxic sesquiterpene lactones (costunolide, parthenolide, and santamarine) and a cytotoxic
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