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diphenylhydantoin/fever

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A trial of diphenylhydantoin in periodic disease (familial Mediterranean fever) in Egyptian children.

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Diphenylhydantoin-induced serum sickness with fibrin-platelet thrombi in lymph node microvasculature.

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In this 16 year old boy a syndrome, characterized by high fever, generalized lymphadenopathy, splenomegaly, diffuse skin rash, facial and periorbital edema, neutropenia, thrombocytopenia, elevated serum glutamic oxaloacetic transaminase (SGOT) levels and transient electrocardiographic changes,

Diphenylhydantoin-induced hepatitis: a case report.

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This case report is of a 25-year old man with severe diphenylhydantoin-induced hepatitis, fever, rash and generalized lymphadenopathy. Hepatic histology and lymphocyte transformation tests strongly supported the diagnosis. He made an uneventful recovery with supportive therapy.

[A case of diphenylhydantoin-induced pneumonitis].

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A 60-year-old man had been administered diphenylhydantoin (DPH) for prevention of convulsive seizures following clipping of an aneurysm of the middle cerebral artery. About one month after the commencement of DPH administration, he developed cough and low grade fever. He was treated with various

Localized cervical lymphadenopathy induced by diphenylhydantoin sodium.

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Diphenylhydantoin sodium is a standard drug in the treatment of convulsive disorders. Numerous untoward reactions have been reported. Lymphadenopathy related to drug-induced hypersensitivity has occurred. A yound woman undergoing treatment for seizures developed a large, tender, localized neck mass,

Mononucleosis and hepatic failure associated with diphenylhydantoin treatment in an infant.

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Diphenylhydantoin-induced hepatitis and mononucleosis are uncommon in children. The occurrence of these two diseases in the same individual, with progression to hepatic failure is rare and has not been reported in infants. This report represents a 6-month-old male infant who developed an infectious

Hepatic injury associated with diphenylhydantoin therapy. A clinicopathologic study of 20 cases.

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Although the toxicity of diphenylhydantoin in a number of target organs is discussed in numberous reports, hepatotoxic reactions are quite rare. The hepatic lesion has mostly been described as necrosis or hepatitis. Tissue sections from 20 patients who had validated diphenylhydantoin hepatotoxicity

[Effect of temperature on the kinetics of propranolol, theophylline, phenytoin and digoxin in rats (author's transl)].

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1. The effect of chronic hyperthermia (35 degree C for 1 month) on the kinetics of propranolol, theophylline, diphenylhydantoin and digoxin was studied in groups of male Wistar rats. 2. Each compound was administered by intravenous injection, dosage being 2 mg/kg for propranolol, 3 mg/kg for

[An elderly case of thrombotic thrombocytopenic purpura].

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A 78-year-old woman was admitted to our hospital because of disorientation and fever on January 21, 1992. Two days before admission she experienced vomiting, anorexia and general malaise. Laboratory examinations on admission disclosed a hemoglobin level of 11.1 g/dl and a platelet count of

[Reactive hemophagocytic syndrome: analysis of a series of 7 cases].

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We report a series of seven patients with reactive hemophagocytic syndrome, which was quite characteristic of its etiological spectrum. Infections were the leading cause, among them a case associated with HIV and another one with Salmonella enteritidis (a hitherto unreported association). The

[Hodgkin's disease following treatment with hydantoins. Report of a case and review of the literature (author's transl)].

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Diagnosis of Hodgkin's disease was made in a patient who had been treated with diphenylhydantoin sodium for 4 years. Three different neoplastic diseases of the lymphoid tissue following therapy with hydantoin derivatives have been reported. Pseudolymphoma is characterized by lymph node enlargement,

[Longitudinal study of patients with febrile convulsive crises].

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This longitudinal study included 113 patients seen through a period of 8 years with febrile convulsive crises, especially of the tonoclonic type, with predominance in males and with average age at the onset of the disease of 6 months. Infectious respiratory processes were considered as the main

Lupus activation with cerebritis following pegylated interferon in a hemodialysis patient.

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BACKGROUND A 20-year-old female patient with chronic hepatitis C virus infection and end-stage renal disease due to systemic lupus erythematosus was admitted to hospital with fever, pain in the abdomen, seizures and an alteration of consciousness. The patient was on maintenance dialysis and was

Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants.

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Drug-induced systemic lupus erythematosus (SLE)-like syndromes in children are most commonly associated with the administration of ethosuximide, diphenylhydantoin, and trimethadione. Five children receiving ethosuximide who presented with syndromes suggestive of SLE were studied. Each and fever,

Impact of phenytoin therapy on the skin and skin disease.

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Phenytoin (diphenylhydantoin; Dilantin), ALZA Corp.) is a highly effective and widely prescribed anticonvulsant agent used in the treatment of focal and tonic clonic generalised seizures. The side effects of phenytoin can occassionally engender significant morbidity. Phenytoin can induce generalised
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