diphenylhydantoin/hemorrhage

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Acquired hemophilia, meningioma, and diphenylhydantoin therapy.

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A patient is reported in whom a meningioma of the lateral one-third of the sphenoid ridge was completely removed and long-term prophylaxis for seizures with diphenylhydantoin was prescribed. One and a half years later, a powerful inhibitor developed that specifically neutralized Factor VIII, the

Cerebral etiology of the acute respiratory distress syndrome: diphenylhydantoin prophylaxis.

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Beagles and rats were subjected to hemorrhage regimens that induced the pulmonary complex of the Acute Respiratory Distress Syndrome (ARDS) in 6:6 dogs and 7:8 rats. Pretreatment with diphenylhydantoin (DPH), 5 mg/kg 1-2 hours preceding hemorrhage, resulted in complete prevention of the lung lesions

[Behavior of nervous tissue during long-term administration of diphenylhydantoin to cats].

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The purpose of the study was to assess the morphological changes in the brain of cats reveiving diphenylhydantoin in therapeutic doses during several weeks. The material included 20 cats: 14 experimental and 6 control. In conditioned behaviour the animals showed a steady reduction in the number of

[Treatment of partial motor status epilepticus in adults with intravenous diphenylhydantoin (DPH). Prospective study of 50 cases].

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Fifty adult patients with partial motor status epilepticus were treated with a single intravenous (i.v.) injection of diphenylhydantoin (DPH), 20 mg/kg body weight at a rate of 1 mg/kg/min. Seizures were controlled in 32 patients (64%) during the injection or within the following hour; in 13 of them

[123I-IMP SPECT findings of visual perseveration in a patient with old hemorrhage in the right occipital lobe].

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We report a case of visual presevertation in a 67-year-old man. He had been well until 66 years of age when he had brain hemorrhage in the right occipital lobe. After an operation for removal of the hematoma, visual hallucination occurred and persisted for about 6 months. One year and a half later,

Pulmonary capillaritis and alveolar hemorrhage. Update on diagnosis and management.

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Pulmonary vascular inflammatory disorders may involve all components of the pulmonary vasculature, including capillaries. The principal histopathologic features of pulmonary capillaritis include capillary wall necrosis with infiltration by neutrophils, interstitial erythrocytes, and/or hemosiderin,

[Effect of diphenylhydantoin sodium in causing deformity and that of folic acid preparations for its prevention].

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Pregnant rats were divided into four groups. The groups A, B and C were intraperitoneally injected with DPH during the 9 to 11 days of gestation in doses of 75 Mg/kg/day. The groups A and B were supplemented with a mixture of folic acid (FA) or with FA alone in the food fed during pregnancy. The

Toxicity and tissue residues from diphenylhydantoin fed to chickens.

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Within three experiments with broiler-type crossbred chickens, diphenlyhydantoin (DPH) was administered via the diet at levels ranging from 10 to 2500 mg./kg. Feed intake and body weight gain were adversely affected by levels of 100 mg./kg. or higher. A hemorrhagic syndrome occurred in 16 percent of

[Sodium diphenylhydantoin as a probable cause of pancreatitis].

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BACKGROUND Drug-induced pancreatitis is much more common in children than in adults. Many drug have been implicated in its pathogenesis. Among the neuropsychiatric drugs only valproic acid, carbamazepine, clozapine and ergotamine have been reported. Phenytoin is commonly used for the treatment of

[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].

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22 patients with severe preeclampsia-eclampsia were treated in our Intensive Care Unit from 1972 to 1978. Control of convulsions was achieved by diazepam, diphenylhydantoin and phenobarbital. In 11 comatose patients brain monitoring was carried out by frequent neurological examination and use of

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