dopa decarboxylase/fatigue

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[Mechanisms of catecholamine synthesis disorders in the adrenals of rats subjected to physical fatigue].

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There was a depression of transformation of noradrenaline, DOPA and thyrosine added in vitro, into catecholamines in the adrenal glands of rats after swimming for a period of 8 hours. This permitted to suppose a depression of the activity of phenylethanolamine-N-methyl-transpherase,

Integrated analysis of droxidopa trials for neurogenic orthostatic hypotension.

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BACKGROUND Droxidopa, a prodrug of norepinephrine, was approved for treatment of neurogenic orthostatic hypotension (nOH) due to primary autonomic disorders based on 3 randomized double-blind studies. We performed safety and efficacy analyses of this pooled dataset (n = 460). METHODS Efficacy was

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