dopamine/edema

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SIRS in Cyanotic and Acyanotic Children in Cardiac Surgery

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Systemic inflammatory response syndrome (SIRS) in adults has been defined as a non-specific systemic inflammatory process in the absence of infection, following incidents such as trauma, burns, pancreatitis, or major surgery. For children, age-specific SIRS criteria were established by the

Caffeine Treatment in in the Delivery Room

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INTRODUCTION Background Mechanical ventilation (MV) is one of the most important risk factors for the development of bronchopulmonary dysplasia (BPD) in the preterm infant, due to the early pulmonary inflammation from volume- and baro-trauma and the secondary 1. Despite this, around 80% of infants

Nilotinib in Huntington's Disease

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The investigators performed an open label phase I clinical trial using two commercially available doses of Nilotinib (150 and 300mg capsules) in patients with advanced PDD and DLB. These indications have some overlapping pathologies and clinical symptoms and share common plasma and CSF biomarkers,

Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)

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Background: Extracorporeal membrane oxygenation (ECMO) is of great value in supporting patients with severe cardiopulmonary failure, but the mortality rate is still high. Acute kidney injury (AKI) and fluid overload (FO) are the leading causes of death in patients under Veno-arterial (VA) ECMO.

Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

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Diabetic retinopathy (DR) and diabetic macular edema (DME) are the primary cause of irreversible blindness and visual impairment in working-age adults. Nearly 80% of patients with diabetes will experience some degree of DR and DME 15-20 years after diagnosis. Altered blood parameters (glucose,

A Controlled Comparison of Two DBS Targets for Upper Extremity Action Tremor

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Tremor is defined as rhythmic and oscillating involuntary movements of a body part. Action tremor occurs when a body part is activated, and is clinically most frequently seen in Essential (idiopathic) Tremor (ET), with an overall prevalence of 0.9 %, and of 4.6 % in people over 65 years. But it can

Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)

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Research design This study is a double blind randomized clinical trial to determine differences in wave amplitude P50 and N95 on pattern ERG examination, visual field defects (LP) with Humphrey HFA (Humphrey Field Analyzer) II-i 750, 24-2 threshold and ganglion cell thickness with OCT CirrusTM

Evaluating the Role of Pregabalin in Reducing Opioid Requirement in Spinal Fusion Surgeries of Two or More Vertebrae

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Introduction Postoperative pain is often thought to be inadequately treated in half of all surgical procedures . Postoperative pain management in patients undergoing spine surgery is often difficult and challenging. The challenges of opioid tolerance and paucity of efficient opioid sparing agents

High-Dose Aldactone for Treatment of Diuretic Resistant Heart Failure

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Congestive heart failure (CHF) is common and currently affects an estimated 6.6 million adults in the United States (1). In addition being highly prevalent, CHF is responsible for ~ 1 million hospital discharges per year and approximately 50% of patients with CHF will die within 5 years making it a

Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus

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The study was approved by the ethic committee of Songklanagarind Hospital in Songkhla, Thailand, and was designed as a randomized, double-blind, placebo-controlled trial. All patients gave their informed consent after receiving written information of the study. Orthopedic patients were invited to

Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects

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The World Health Organization (WHO) estimates that more than 180 million people worldwide have diabetes. This number is likely to more than double by 2030. Further, the WHO proclaims that diabetes causes about 5 % of all deaths globally each year. Cardiovascular events are the most common cause for

Select Stim: Selective Stimulation of the Subthalamic Nucleus in Parkinson's Disease. "A Feasibility Study"

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Parkinson disease (PD) is a common neurodegenerative disorder, characterized by motor symptoms. Patients are initially treated successfully with drugs (e.g. levodopa), unfortunately use is limited due to severe side effects. In the advanced stages of PD neurosurgical treatment is the next

Impact of Switching to Continuous Release Dopamine Agonists

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The purpose of this proposal is to determine if switching PD patients treated with pramipexole to ropinirole CR reduces the non-motor side effects frequently experienced by these patients. Side effects that we will monitor in particular include somnolence, peripheral edema, cognitive decline with

Prevention of Contrast Nephropathy by Sodium Bicarbonate Versus Sodium Chloride and N-acetylcysteine

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PROTOCOL Prevention of Contrast Nephropathy by Sodium Bicarbonate Versus Sodium Chloride and N-Acetylcysteine Nephrology and Cardiology Services, Shaare Zedek Medical Center, Jerusalem 1. Background and rationale The development of acute renal failure following cardiac catheterization has been

SWITCH:Restless Legs Patients Switched to Ropinirole From Pramipexole

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BACKGROUND Dopamine agonists such as ropinirole (Requip) and pramipexole (Mirapex) are effective treatments for Restless Legs Syndrome and Parkinson Disease. However, although the safety and efficacy may be established, it is common for clinicians to switch between therapies in order to seek optimal

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