drimys andina/antifungal

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Antifungal activity of drimane sesquiterpenes from Drimys brasiliensis using bioassay-guided fractionation.

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OBJECTIVE This study describes the antifungal effect of extracts and compounds isolated from Drimys brasiliensis acting against dermatophytes. METHODS The activities were evaluated by using the microbroth dilution method. RESULTS Bioassay-guided fractionation of the most active extract from the bark

Antifungal effects of drimane sesquiterpenoids isolated from Drimys winteri against Gaeumannomyces graminis var. tritici

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Gaeumannomyces graminis var. tritici (Ggt) is a soil-borne pathogen which causes 'take-all' disease affecting cereal roots. In wheat, Ggt is the most important biotic factor causing around 30-50% of yield losses. The chemical control of this fungal disease is difficult, due to Ggt is able to

Anti-leishmanial and anti-trypanosomal potential of polygodial isolated from stem barks of Drimys brasiliensis Miers (Winteraceae).

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Parasitic protozoan diseases affect the poorest population in developing countries. Leishmaniasis and Chagas disease have been included among the most important threats for public health in Central and South American continent, with few therapeutic alternatives and highly toxic drugs. In the course

Oxidation of Isodrimeninol with PCC Yields Drimane Derivatives with Activity against Candida Yeast by Inhibition of Lanosterol 14-Alpha Demethylase

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Candida species cause an opportunistic yeast infection called Candidiasis, which is responsible for more than 50,000 deaths every year around the world. Effective treatments against candidiasis caused by non-albicans Candida species such as C. glabrata, C. parapsilosis, C.

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